DegronMD - Q96KJ4(MSLNL)

GO - Biological processes (BP): View more >>

GO - Molecular function (MF): View more >>

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.S622L	TCGA-AC-A3W5	BRCA	TCGA	PPSTT	DEG_SPOP_SBC_1	608:612	Mutation rewiring degron network	0.0556
p.S622L	TCGA-DA-A1HW	SKCM	TCGA	PPSTT	DEG_SPOP_SBC_1	608:612	Mutation rewiring degron network	0.0556
p.S622L	DO49024	BRCA	ICGC	PPSTT	DEG_SPOP_SBC_1	608:612	Mutation rewiring degron network	0.0556
p.S622L	DO220881	MELA	ICGC	PPSTT	DEG_SPOP_SBC_1	608:612	Mutation rewiring degron network	0.0556
p.S622L	DO38129	SKCM	ICGC	PPSTT	DEG_SPOP_SBC_1	608:612	Mutation rewiring degron network	0.0556
p.A605V	TCGA-LI-A67I	SARC	TCGA	PPSTT	DEG_SPOP_SBC_1	608:612	Mutation rewiring degron network	0.25
p.A605V	DO220201	SARC	ICGC	PPSTT	DEG_SPOP_SBC_1	608:612	Mutation rewiring degron network	0.25
p.P608S	ACH-000409	Ovarian Cancer	CCLE	PPSTT	DEG_SPOP_SBC_1	608:612	Mutation altering degron motif	0.6752

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons