DegronMD - Q96KN9(GJD4)

GO - Biological processes (BP): View more >>

GO - Molecular function (MF): View more >>

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.A359D	TCGA-CM-6171	COAD	TCGA	PASSS	DEG_SPOP_SBC_1	353:357	Mutation rewiring degron network	0.2778
p.A359D	DO8151	COAD	ICGC	PASSS	DEG_SPOP_SBC_1	353:357	Mutation rewiring degron network	0.2778
p.A364S	TCGA-OR-A5JA	ACC	TCGA	PASSS	DEG_SPOP_SBC_1	353:357	Mutation rewiring degron network	0.1389
p.A359T	DO229248	THCA	ICGC	PASSS	DEG_SPOP_SBC_1	353:357	Mutation rewiring degron network	0.2778
p.S346R	ACH-000431	Lung Cancer	CCLE	PASSS	DEG_SPOP_SBC_1	353:357	Mutation rewiring degron network	0.1389
p.D351V	ACH-000790	Lung Cancer	CCLE	PASSS	DEG_SPOP_SBC_1	353:357	Mutation rewiring degron network	0.2778
p.P349S	ACH-001698	Head and Neck Cancer	CCLE	PASSS	DEG_SPOP_SBC_1	353:357	Mutation rewiring degron network	0.2222

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons