DegronMD - Q96M61(MAGEB18)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.T70A	TCGA-19-2624	GBM	TCGA	APSTT	DEG_SPOP_SBC_1	67:71	Mutation altering degron motif	0.7139
p.T70A	DO14049	GBM	ICGC	APSTT	DEG_SPOP_SBC_1	67:71	Mutation altering degron motif	0.7139
p.S69Y	TCGA-49-AARQ	LUAD	TCGA	APSTT	DEG_SPOP_SBC_1	67:71	Mutation altering degron motif	0.712
p.S69Y	DO51189	LUAD	ICGC	APSTT	DEG_SPOP_SBC_1	67:71	Mutation altering degron motif	0.712
p.A67T	TCGA-C5-A7UE	CESC	TCGA	APSTT	DEG_SPOP_SBC_1	67:71	Mutation altering degron motif	0.7139
p.A67T	DO49890	CESC	ICGC	APSTT	DEG_SPOP_SBC_1	67:71	Mutation altering degron motif	0.7139
p.P58H	TCGA-G7-6795	KIRP	TCGA	APSTT	DEG_SPOP_SBC_1	67:71	Mutation rewiring degron network	0.0833
p.P58H	DO20851	KIRP	ICGC	APSTT	DEG_SPOP_SBC_1	67:71	Mutation rewiring degron network	0.0833
p.P58H	SIDM00500	Colorectal Carcinoma	GDSC	APSTT	DEG_SPOP_SBC_1	67:71	Mutation rewiring degron network	0.0833
p.P58H	ACH-000959	Colon/Colorectal Cancer	CCLE	APSTT	DEG_SPOP_SBC_1	67:71	Mutation rewiring degron network	0.0833
p.S81L	DO229341	BTCA	ICGC	APSTT	DEG_SPOP_SBC_1	67:71	Mutation rewiring degron network	0.0556
p.P68Q	DO231127	LUSC	ICGC	APSTT	DEG_SPOP_SBC_1	67:71	Mutation altering degron motif	0.5924

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons