DegronMD - Q96M89(CCDC138)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.E108K	TCGA-DQ-5631	HNSC	TCGA	DYR	CBL_MET	113:115	Mutation rewiring degron network	0.1944
p.E108K	DO14175	HNSC	ICGC	DYR	CBL_MET	113:115	Mutation rewiring degron network	0.1944
p.R115T	DO225367	BRCA	ICGC	DYR	CBL_MET	113:115	Mutation altering degron motif	0.7876
p.T122S	DO222501	COCA	ICGC	DYR	CBL_MET	113:115	Mutation rewiring degron network	0.1389
p.E107Q	DO222764	ESCA	ICGC	DYR	CBL_MET	113:115	Mutation rewiring degron network	0.1667
p.R115K	DO229489	LAML	ICGC	DYR	CBL_MET	113:115	Mutation altering degron motif	0.7237
p.E108D	DO229045	LICA	ICGC	DYR	CBL_MET	113:115	Mutation rewiring degron network	0.1944
p.D113Y	DO23330	LINC	ICGC	DYR	CBL_MET	113:115	Mutation altering degron motif	0.7325
p.D113G	DO23330	LINC	ICGC	DYR	CBL_MET	113:115	Mutation altering degron motif	0.7198
p.D113G	SIDM01777	Pancreatic Carcinoma	GDSC	DYR	CBL_MET	113:115	Mutation altering degron motif	0.7198

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons