DegronMD - Q96PG2(MS4A10)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.D233N	TCGA-4Z-AA89	BLCA	TCGA	PPSY	ITCH	223:226	Mutation rewiring degron network	0.1389
p.D233N	DO218991	BLCA	ICGC	PPSY	ITCH	223:226	Mutation rewiring degron network	0.1389
p.D233N	DO50319	ESAD	ICGC	PPSY	ITCH	223:226	Mutation rewiring degron network	0.1389
p.G232S	TCGA-93-A4JO	LUAD	TCGA	PPSY	ITCH	223:226	Mutation rewiring degron network	0.1667
p.G232S	DO51194	LUAD	ICGC	PPSY	ITCH	223:226	Mutation rewiring degron network	0.1667
p.L215I	TCGA-A5-A0G2	UCEC	TCGA	PPSY	ITCH	223:226	Mutation rewiring degron network	0.1111
p.L215I	DO41235	UCEC	ICGC	PPSY	ITCH	223:226	Mutation rewiring degron network	0.1111
p.Q227H	TCGA-AC-A23H	BRCA	TCGA	PPSY	ITCH	223:226	Mutation rewiring degron network	0.3056
p.Q227H	DO2401	BRCA	ICGC	PPSY	ITCH	223:226	Mutation rewiring degron network	0.3056
p.I230T	TCGA-AP-A059	UCEC	TCGA	PPSY	ITCH	223:226	Mutation rewiring degron network	0.2222
p.I230T	DO41361	UCEC	ICGC	PPSY	ITCH	223:226	Mutation rewiring degron network	0.2222
p.P222S	TCGA-GM-A3XL	BRCA	TCGA	PPSY	ITCH	223:226	Mutation rewiring degron network	0.3056
p.P222S	DO44111	BRCA	ICGC	PPSY	ITCH	223:226	Mutation rewiring degron network	0.3056
p.P223L	TCGA-L5-A88S	ESCA	TCGA	PPSY	ITCH	223:226	Mutation altering degron motif	0.7582
p.P223L	TCGA-MP-A4T2	LUAD	TCGA	PPSY	ITCH	223:226	Mutation altering degron motif	0.7582
p.P223L	DO45378	LUAD	ICGC	PPSY	ITCH	223:226	Mutation altering degron motif	0.7582
p.Q235P	SIDM02059	Colorectal Carcinoma	GDSC	PPSY	ITCH	223:226	Mutation rewiring degron network	0.0833
p.A234T	SIDM00438	B-Lymphoblastic Leukemia	GDSC	PPSY	ITCH	223:226	Mutation rewiring degron network	0.1111
p.A234T	ACH-002275	Leukemia	CCLE	PPSY	ITCH	223:226	Mutation rewiring degron network	0.1111
p.A234T	MN-60	haematopoietic and lymphoid tissue	COSMIC	PPSY	ITCH	223:226	Mutation rewiring degron network	0.1111

Kaplan plot for MS4A10 in

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons

MS4A10

UniProt ID: Q96PG2

Entrez ID: 341116

Protein name: Membrane-spanning 4-domains subfamily A member 10 (CD20 antigen-like 7)

External links: UniprotKB HGNC RefSeq COSMIC

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Kaplan plot for MS4A10 in