DegronMD - Q99567(NUP88)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.A43V	TCGA-12-0618	GBM	TCGA	PASSS	DEG_SPOP_SBC_1	42:46	Mutation altering degron motif	0.5825
p.A43V	DO14001	GBM	ICGC	PASSS	DEG_SPOP_SBC_1	42:46	Mutation altering degron motif	0.5825
p.P53L	TCGA-BA-A6D8	HNSC	TCGA	PASSS	DEG_SPOP_SBC_1	42:46	Mutation rewiring degron network	0.1389
p.P53L	DO44426	HNSC	ICGC	PASSS	DEG_SPOP_SBC_1	42:46	Mutation rewiring degron network	0.1389
p.N33S	TCGA-CA-6717	COAD	TCGA	PASSS	DEG_SPOP_SBC_1	42:46	Mutation rewiring degron network	0.0833
p.N33S	DO8264	COAD	ICGC	PASSS	DEG_SPOP_SBC_1	42:46	Mutation rewiring degron network	0.0833
p.P42S	TCGA-D3-A8GR	SKCM	TCGA	PASSS	DEG_SPOP_SBC_1	42:46	Mutation altering degron motif	0.6752
p.P42S	DO51247	SKCM	ICGC	PASSS	DEG_SPOP_SBC_1	42:46	Mutation altering degron motif	0.6752
p.P42S	ACH-001061	Colon/Colorectal Cancer	CCLE	PASSS	DEG_SPOP_SBC_1	42:46	Mutation altering degron motif	0.6752
p.P51S	TCGA-D5-6930	COAD	TCGA	PASSS	DEG_SPOP_SBC_1	42:46	Mutation rewiring degron network	0.1944
p.P51S	DO10550	COAD	ICGC	PASSS	DEG_SPOP_SBC_1	42:46	Mutation rewiring degron network	0.1944
p.P51S	DO233865	GACA	ICGC	PASSS	DEG_SPOP_SBC_1	42:46	Mutation rewiring degron network	0.1944
p.P36S	TCGA-FR-A8YC	SKCM	TCGA	PASSS	DEG_SPOP_SBC_1	42:46	Mutation rewiring degron network	0.1667
p.P36S	TCGA-YC-A89H	BLCA	TCGA	PASSS	DEG_SPOP_SBC_1	42:46	Mutation rewiring degron network	0.1667
p.P36S	DO51948	BLCA	ICGC	PASSS	DEG_SPOP_SBC_1	42:46	Mutation rewiring degron network	0.1667
p.P36S	DO50301	SKCM	ICGC	PASSS	DEG_SPOP_SBC_1	42:46	Mutation rewiring degron network	0.1667
p.E38K	TCGA-GM-A2D9	BRCA	TCGA	PASSS	DEG_SPOP_SBC_1	42:46	Mutation rewiring degron network	0.2222
p.E38K	DO4810	BRCA	ICGC	PASSS	DEG_SPOP_SBC_1	42:46	Mutation rewiring degron network	0.2222
p.P48S	DO228955	LICA	ICGC	PASSS	DEG_SPOP_SBC_1	42:46	Mutation rewiring degron network	0.2778
p.P48S	ACH-000737	Lung Cancer	CCLE	PASSS	DEG_SPOP_SBC_1	42:46	Mutation rewiring degron network	0.2778

Kaplan plot for NUP88 in

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons

NUP88

UniProt ID: Q99567

Entrez ID: 4927

Protein name: Nuclear pore complex protein Nup88 (88 kDa nucleoporin) (Nucleoporin Nup88)

External links: UniprotKB HGNC RefSeq COSMIC

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Kaplan plot for NUP88 in