FEV
UniProt ID: Q99581
Entrez ID: 54738
Protein name: Protein FEV (Fifth Ewing variant protein) (PC12 ETS domain-containing transcription factor 1) (PC12 ETS factor 1) (Pet-1)
External links: UniprotKB HGNC RefSeq COSMIC
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FUNCTION: Functions as a transcriptional regulator. According to PubMed:12761502, it functions as a transcriptional repressor. Functions in the differentiation and the maintenance of the central serotonergic neurons. May play a role in cell growth. {ECO:0000269|PubMed:12761502}....
FUNCTION: Functions as a transcriptional regulator. According to PubMed:12761502, it functions as a transcriptional repressor. Functions in the differentiation and the maintenance of the central serotonergic neurons. May play a role in cell growth. {ECO:0000269|PubMed:12761502}.
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GO - Biological processes (BP):
cell differentiation [GO:0030154]; neuron fate specification [GO:0048665]; neuron maturation [GO:0042551]; positive regulation of gene expression [GO:0010628]; regulation of transcription by RNA polymerase II [GO:0006357]...
cell differentiation [GO:0030154]; neuron fate specification [GO:0048665]; neuron maturation [GO:0042551]; positive regulation of gene expression [GO:0010628]; regulation of transcription by RNA polymerase II [GO:0006357]
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GO - Molecular function (MF):
DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; sequence-specific double-stranded DNA binding...
DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; RNA polymerase II cis-regulatory region sequence-specific DNA binding [GO:0000978]; sequence-specific double-stranded DNA binding [GO:1990837]
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GO - Cellular component (CC):
chromatin [GO:0000785]; nuclear speck [GO:0016607]; nucleus [GO:0005634]...
chromatin [GO:0000785]; nuclear speck [GO:0016607]; nucleus [GO:0005634]
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FEV
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Kaplan plot for FEV in
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*NOTE: the Kaplan plots were collected from OncoLnc