DegronMD - Q99732(LITAF)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.G50R	TCGA-21-1079	LUSC	TCGA	PPSY	ITCH	58:61	Mutation rewiring degron network	0.1111
p.G50R	DO26846	LUSC	ICGC	PPSY	ITCH	58:61	Mutation rewiring degron network	0.1111
p.V27M	TCGA-2W-A8YY	CESC	TCGA	PPSY	ITCH	20:23	Mutation rewiring degron network	0.2222
p.V27M	DO223732	CESC	ICGC	PPSY	ITCH	20:23	Mutation rewiring degron network	0.2222
p.S15L	TCGA-4Z-AA80	BLCA	TCGA	PPSY	ITCH	20:23	Mutation rewiring degron network	0.1944
p.S15L	DO218986	BLCA	ICGC	PPSY	ITCH	20:23	Mutation rewiring degron network	0.1944
p.V29F	TCGA-CN-5360	HNSC	TCGA	PPSY	ITCH	20:23	Mutation rewiring degron network	0.1667
p.V29F	DO14662	HNSC	ICGC	PPSY	ITCH	20:23	Mutation rewiring degron network	0.1667
p.G53W	TCGA-D3-A2JK	SKCM	TCGA	PPSY	ITCH	58:61	Mutation rewiring degron network	0.1944
p.G53W	DO37619	SKCM	ICGC	PPSY	ITCH	58:61	Mutation rewiring degron network	0.1944
p.G50W	TCGA-EY-A215	UCEC	TCGA	PPSY	ITCH	58:61	Mutation rewiring degron network	0.1111
p.G50W	DO42665	UCEC	ICGC	PPSY	ITCH	58:61	Mutation rewiring degron network	0.1111
p.P20S	TCGA-FF-8043	DLBC	TCGA	PPSY	ITCH	20:23	Mutation altering degron motif	0.6752
p.P20S	DO222308	DLBC	ICGC	PPSY	ITCH	20:23	Mutation altering degron motif	0.6752
p.A19T	TCGA-FI-A2D5	UCEC	TCGA	PPSY	ITCH	20:23	Mutation rewiring degron network	0.3056
p.A19T	DO41331	UCEC	ICGC	PPSY	ITCH	20:23	Mutation rewiring degron network	0.3056
p.A19T	ACH-000960	Leukemia	CCLE	PPSY	ITCH	20:23	Mutation rewiring degron network	0.3056
p.S18Y	DO229027	LICA	ICGC	PPSY	ITCH	20:23	Mutation rewiring degron network	0.2778
p.A19E	DO229027	LICA	ICGC	PPSY	ITCH	20:23	Mutation rewiring degron network	0.3056
p.A66V	DO229078	PRAD	ICGC	PPSY	ITCH	58:61	Mutation rewiring degron network	0.1944
p.N57D	SIDM01314	Colorectal Carcinoma	GDSC	PPSY	ITCH	58:61	Mutation rewiring degron network	0.3056

Kaplan plot for LITAF in

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons

LITAF

UniProt ID: Q99732

Entrez ID: 9516

Protein name: Lipopolysaccharide-induced tumor necrosis factor-alpha factor (LPS-induced TNF-alpha factor) (Small integral membrane protein of lysosome/late endosome) (p53-induced gene 7 protein)

External links: UniprotKB HGNC RefSeq COSMIC

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Kaplan plot for LITAF in