DegronMD - Q99932(SPAG8)

SPAG8

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.T129A	TCGA-86-A4JF	LUAD	TCGA	PGSSS	DEG_SPOP_SBC_1	139:143	Mutation rewiring degron network	0.0556
p.V146A	TCGA-AP-A0LM	UCEC	TCGA	PGSSS	DEG_SPOP_SBC_1	139:143	Mutation rewiring degron network	0.25
p.E379K	TCGA-ED-A4XI	LIHC	TCGA	DYR	CBL_MET	385:387	Mutation rewiring degron network	0.1667
p.E377D	TCGA-OR-A5JA	ACC	TCGA	DYR	CBL_MET	385:387	Mutation rewiring degron network	0.1111
p.R385Q	DO7018	CLLE	ICGC	DYR	CBL_MET	385:387	Mutation altering degron motif	0.7329
p.P133T	DO229034	LICA	ICGC	PGSSS	DEG_SPOP_SBC_1	139:143	Mutation rewiring degron network	0.1667
p.E377K	DO48505	LIHC	ICGC	DYR	CBL_MET	385:387	Mutation rewiring degron network	0.1111
p.E375G	DO228373	MALY	ICGC	DYR	CBL_MET	385:387	Mutation rewiring degron network	0.0556
p.P396S	DO47584	SKCM	ICGC	DYR	CBL_MET	385:387	Mutation rewiring degron network	0.0833
p.V144A	DO43306	UCEC	ICGC	PGSSS	DEG_SPOP_SBC_1	139:143	Mutation rewiring degron network	0.3056

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*NOTE: the Kaplan plots were collected from OncoLnc