DegronMD - Q99954(SMR3A)

FUNCTION: May play a role in protection or detoxification. {ECO:0000250}.

GO - Biological processes (BP): regulation of sensory perception of pain [GO:0051930]

GO - Molecular function (MF): endopeptidase inhibitor activity [GO:0004866]

GO - Cellular component (CC): extracellular region [GO:0005576]

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.P96H	SIDM00743	Non-Small Cell Lung Carcinoma	GDSC	PPPY	ITCH	95:98	Mutation altering degron motif	0.7694
p.P96H	ACH-000448	Lung Cancer	CCLE	PPPY	ITCH	95:98	Mutation altering degron motif	0.7694
p.P96H	NCI-H1666	lung	COSMIC	PPPY	ITCH	95:98	Mutation altering degron motif	0.7694
p.P81L	TCGA-06-5416	GBM	TCGA	PPPY	ITCH	81:84	Mutation altering degron motif	0.7582
p.P81L	DO10880	GBM	ICGC	PPPY	ITCH	81:84	Mutation altering degron motif	0.7582
p.P56L	TCGA-D3-A8GM	SKCM	TCGA	PPPY	ITCH	55:58	Mutation altering degron motif	0.7582
p.P56L	DO50288	SKCM	ICGC	PPPY	ITCH	55:58	Mutation altering degron motif	0.7582
p.P81T	TCGA-NJ-A4YF	LUAD	TCGA	PPPY	ITCH	81:84	Mutation altering degron motif	0.7031
p.P81T	DO218940	LUAD	ICGC	PPPY	ITCH	81:84	Mutation altering degron motif	0.7031
p.P56S	TCGA-D3-A8GM	SKCM	TCGA	PPPY	ITCH	55:58	Mutation altering degron motif	0.6752
p.P56S	DO50288	SKCM	ICGC	PPPY	ITCH	55:58	Mutation altering degron motif	0.6752
p.P95S	TCGA-EE-A29E	SKCM	TCGA	PPPY	ITCH	95:98	Mutation altering degron motif	0.6752
p.P95S	TCGA-EE-A2MS	SKCM	TCGA	PPPY	ITCH	95:98	Mutation altering degron motif	0.6752
p.P95S	DO37567	SKCM	ICGC	PPPY	ITCH	95:98	Mutation altering degron motif	0.6752
p.P95S	DO37831	SKCM	ICGC	PPPY	ITCH	95:98	Mutation altering degron motif	0.6752
p.P96S	DO233161	GACA	ICGC	PPPY	ITCH	95:98	Mutation altering degron motif	0.6752
p.P97S	TCGA-EB-A3Y7	SKCM	TCGA	PPPY	ITCH	95:98	Mutation altering degron motif	0.5641
p.P97S	TCGA-ER-A42L	SKCM	TCGA	PPPY	ITCH	95:98	Mutation altering degron motif	0.5641
p.P97S	DO37499	SKCM	ICGC	PPPY	ITCH	95:98	Mutation altering degron motif	0.5641
p.P97S	DO223910	SKCM	ICGC	PPPY	ITCH	95:98	Mutation altering degron motif	0.5641

Showing 1 to 20 of 124 entries

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Kaplan plot for SMR3A in

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons

SMR3A

UniProt ID: Q99954

Entrez ID: 26952

Protein name: Submaxillary gland androgen-regulated protein 3A (Proline-rich protein 5) (Proline-rich protein PBI)

External links: UniprotKB HGNC RefSeq COSMIC

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Kaplan plot for SMR3A in