DegronMD - Q9BSE2(TMEM79)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.A382V	TCGA-DK-A1AB	BLCA	TCGA	DYR	CBL_MET	387:389	Mutation rewiring degron network	0.1944
p.A382V	DO461	BLCA	ICGC	DYR	CBL_MET	387:389	Mutation rewiring degron network	0.1944
p.D377Y	DO228948	LICA	ICGC	DYR	CBL_MET	387:389	Mutation rewiring degron network	0.0556
p.D377Y	DO229035	LICA	ICGC	DYR	CBL_MET	387:389	Mutation rewiring degron network	0.0556
p.D387Y	DO229045	LICA	ICGC	DYR	CBL_MET	387:389	Mutation altering degron motif	0.7325
p.R383L	DO229006	LICA	ICGC	DYR	CBL_MET	387:389	Mutation rewiring degron network	0.2222
p.P392L	DO231868	LINC	ICGC	DYR	CBL_MET	387:389	Mutation rewiring degron network	0.25
p.R383P	DO46528	OV	ICGC	DYR	CBL_MET	387:389	Mutation rewiring degron network	0.2222
p.P379L	SIDM00232	Kidney Carcinoma	GDSC	DYR	CBL_MET	387:389	Mutation rewiring degron network	0.1111
p.P379L	NCC021	kidney	COSMIC	DYR	CBL_MET	387:389	Mutation rewiring degron network	0.1111
p.A382T	SIDM01007	T-Lymphoblastic Leukemia	GDSC	DYR	CBL_MET	387:389	Mutation rewiring degron network	0.1944
p.A382T	ACH-002256	Leukemia	CCLE	DYR	CBL_MET	387:389	Mutation rewiring degron network	0.1944
p.A382T	KARPAS-45	haematopoietic and lymphoid tissue	COSMIC	DYR	CBL_MET	387:389	Mutation rewiring degron network	0.1944
p.P379S	ACH-000773	Lymphoma	CCLE	DYR	CBL_MET	387:389	Mutation rewiring degron network	0.1111
p.Y378S	ACH-002225	Brain Cancer	CCLE	DYR	CBL_MET	387:389	Mutation rewiring degron network	0.0833

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons