DegronMD - Q9BTE0(NAT9)

NAT9

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.Q163H	TCGA-D3-A2JP	SKCM	TCGA	VATSS	DEG_SPOP_SBC_1	164:168	Mutation rewiring degron network	0.3056
p.Q163H	DO47407	SKCM	ICGC	VATSS	DEG_SPOP_SBC_1	164:168	Mutation rewiring degron network	0.3056
p.L177P	TCGA-D8-A1XK	BRCA	TCGA	VATSS	DEG_SPOP_SBC_1	164:168	Mutation rewiring degron network	0.0833
p.L177P	DO4749	BRCA	ICGC	VATSS	DEG_SPOP_SBC_1	164:168	Mutation rewiring degron network	0.0833
p.T166M	TCGA-EY-A1H0	UCEC	TCGA	VATSS	DEG_SPOP_SBC_1	164:168	Mutation altering degron motif	0.7423
p.T166M	TCGA-L5-A4OS	ESCA	TCGA	VATSS	DEG_SPOP_SBC_1	164:168	Mutation altering degron motif	0.7423
p.T166M	DO43114	UCEC	ICGC	VATSS	DEG_SPOP_SBC_1	164:168	Mutation altering degron motif	0.7423
p.F156L	TCGA-IR-A3LH	CESC	TCGA	VATSS	DEG_SPOP_SBC_1	164:168	Mutation rewiring degron network	0.1111
p.F156L	DO44381	CESC	ICGC	VATSS	DEG_SPOP_SBC_1	164:168	Mutation rewiring degron network	0.1111
p.R159Q	SIDM00216	Colorectal Carcinoma	GDSC	VATSS	DEG_SPOP_SBC_1	164:168	Mutation rewiring degron network	0.1944
p.R159Q	SNU-175	large intestine	COSMIC	VATSS	DEG_SPOP_SBC_1	164:168	Mutation rewiring degron network	0.1944
p.R154Q	ACH-000989	Colon/Colorectal Cancer	CCLE	VATSS	DEG_SPOP_SBC_1	164:168	Mutation rewiring degron network	0.0556
p.R154Q	SNU-175	large intestine	COSMIC	VATSS	DEG_SPOP_SBC_1	164:168	Mutation rewiring degron network	0.0556
p.R158Q	SNU-175	large intestine	COSMIC	VATSS	DEG_SPOP_SBC_1	164:168	Mutation substituting flanking lysine	0.2778

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*NOTE: the Kaplan plots were collected from OncoLnc