DegronMD - Q9BTU6(PI4K2A)

PI4K2A

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.S5N	TCGA-69-7763	LUAD	TCGA	PPDY	ITCH	15:18	Mutation blocking phosphorylation signal	0.5
p.S5N	DO24616	LUAD	ICGC	PPDY	ITCH	15:18	Mutation blocking phosphorylation signal	0.5
p.V6G	TCGA-A5-A1OF	UCEC	TCGA	PPDY	ITCH	15:18	Mutation rewiring degron network	0.0833
p.V6G	DO42568	UCEC	ICGC	PPDY	ITCH	15:18	Mutation rewiring degron network	0.0833
p.P21S	TCGA-MI-A75C	LIHC	TCGA	PPDY	ITCH	15:18	Mutation rewiring degron network	0.25
p.P21S	DO49705	LIHC	ICGC	PPDY	ITCH	15:18	Mutation rewiring degron network	0.25
p.Q5H	DO222798	COCA	ICGC	PPDY	ITCH	15:18	Mutation blocking phosphorylation signal	0.5
p.R11M	DO229036	LICA	ICGC	PPDY	ITCH	15:18	Mutation rewiring degron network	0.2222
p.W7R	DO50783	LIRI	ICGC	PPDY	ITCH	15:18	Mutation rewiring degron network	0.1111
p.S5T	DO228424	MALY	ICGC	PPDY	ITCH	15:18	Mutation blocking phosphorylation signal	0.5
p.V22L	DO27909	ORCA	ICGC	PPDY	ITCH	15:18	Mutation rewiring degron network	0.2222
p.P10S	ACH-000958	Colon/Colorectal Cancer	CCLE	PPDY	ITCH	15:18	Mutation rewiring degron network	0.1944

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*NOTE: the Kaplan plots were collected from OncoLnc