DegronMD - Q9BTX7(TTPAL)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.E19K	TCGA-KQ-A41R	BLCA	TCGA	PPGY	ITCH	28:31	Mutation rewiring degron network	0.0833
p.E19K	DO223592	BLCA	ICGC	PPGY	ITCH	28:31	Mutation rewiring degron network	0.0833
p.C33Y	SIDM00364	B-Lymphoblastic Leukemia	GDSC	PPGY	ITCH	28:31	Mutation rewiring degron network	0.2778
p.C33Y	ACH-002059	Leukemia	CCLE	PPGY	ITCH	28:31	Mutation rewiring degron network	0.2778
p.C33Y	P30-OHK	haematopoietic and lymphoid tissue	COSMIC	PPGY	ITCH	28:31	Mutation rewiring degron network	0.2778
p.Y31C	SIDM00282	Colorectal Carcinoma	GDSC	PPGY	ITCH	28:31	Mutation altering degron motif	0.7087
p.Y31C	ACH-000998	Colon/Colorectal Cancer	CCLE	PPGY	ITCH	28:31	Mutation altering degron motif	0.7087
p.Y31C	CW-2	large intestine	COSMIC	PPGY	ITCH	28:31	Mutation altering degron motif	0.7087

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons