DegronMD - Q9BUH8(BEGAIN)

GO - Biological processes (BP): View more >>

GO - Molecular function (MF): View more >>

GO - Cellular component (CC): View more >>

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.A305T	TCGA-DU-6392	LGG	TCGA	PTSSS	DEG_SPOP_SBC_1	295:299	Mutation rewiring degron network	0.1667
p.F303L	TCGA-ND-A4WC	UCS	TCGA	PTSSS	DEG_SPOP_SBC_1	295:299	Mutation rewiring degron network	0.2222
p.A293V	DO233291	GACA	ICGC	PTSSS	DEG_SPOP_SBC_1	295:299	Mutation rewiring degron network	0.2778
p.A293V	DO41572	UCEC	ICGC	PTSSS	DEG_SPOP_SBC_1	295:299	Mutation rewiring degron network	0.2778
p.A288D	DO228288	LICA	ICGC	PTSSS	DEG_SPOP_SBC_1	295:299	Mutation rewiring degron network	0.1389
p.G305E	DO37719	SKCM	ICGC	PTSSS	DEG_SPOP_SBC_1	295:299	Mutation rewiring degron network	0.1667
p.A291T	DO38380	STAD	ICGC	PTSSS	DEG_SPOP_SBC_1	295:299	Mutation rewiring degron network	0.2222
p.S289R	SIDM02021	Esophageal Carcinoma	GDSC	PTSSS	DEG_SPOP_SBC_1	295:299	Mutation rewiring degron network	0.1667
p.E285K	SIDM00429	B-Lymphoblastic Leukemia	GDSC	PTSSS	DEG_SPOP_SBC_1	295:299	Mutation rewiring degron network	0.0556
p.E285K	ACH-000938	Leukemia	CCLE	PTSSS	DEG_SPOP_SBC_1	295:299	Mutation rewiring degron network	0.0556
p.G301D	SNU-1040	large intestine	COSMIC	PTSSS	DEG_SPOP_SBC_1	295:299	Mutation rewiring degron network	0.2778

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons