DegronMD - Q9BWG4(SSBP4)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.S254C	TCGA-DK-A3IN	BLCA	TCGA	PYSSS	DEG_SPOP_SBC_1	252:256	Mutation altering degron motif	0.7541
p.S254C	DO455	BLCA	ICGC	PYSSS	DEG_SPOP_SBC_1	252:256	Mutation altering degron motif	0.7541
p.G259V	TCGA-FI-A2D0	UCEC	TCGA	PYSSS	DEG_SPOP_SBC_1	252:256	Mutation rewiring degron network	0.25
p.G259V	DO43891	UCEC	ICGC	PYSSS	DEG_SPOP_SBC_1	252:256	Mutation rewiring degron network	0.25
p.S256L	TCGA-GM-A2D9	BRCA	TCGA	PYSSS	DEG_SPOP_SBC_1	252:256	Mutation altering degron motif	0.7667
p.S256L	DO4810	BRCA	ICGC	PYSSS	DEG_SPOP_SBC_1	252:256	Mutation altering degron motif	0.7667
p.S256L	ACH-000927	Breast Cancer	CCLE	PYSSS	DEG_SPOP_SBC_1	252:256	Mutation altering degron motif	0.7667
p.S245N	SIDM00651	Non-Small Cell Lung Carcinoma	GDSC	PYSSS	DEG_SPOP_SBC_1	252:256	Mutation rewiring degron network	0.1389
p.S245N	NCI-H1155	lung	COSMIC	PYSSS	DEG_SPOP_SBC_1	252:256	Mutation rewiring degron network	0.1389

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons