DegronMD - Q9BXG8(SPZ1)

SPZ1

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.S425L	TCGA-97-A4M5	LUAD	TCGA	SLR	DEG_APCC_TPR_1	428:430	Mutation rewiring degron network	0.25
p.S425L	DO218938	LUAD	ICGC	SLR	DEG_APCC_TPR_1	428:430	Mutation rewiring degron network	0.25
p.L419I	TCGA-AP-A059	UCEC	TCGA	SLR	DEG_APCC_TPR_1	428:430	Mutation rewiring degron network	0.0833
p.L419I	DO41361	UCEC	ICGC	SLR	DEG_APCC_TPR_1	428:430	Mutation rewiring degron network	0.0833
p.R430I	TCGA-B5-A0JT	UCEC	TCGA	SLR	DEG_APCC_TPR_1	428:430	Mutation altering degron motif	0.8102
p.R430I	DO40802	UCEC	ICGC	SLR	DEG_APCC_TPR_1	428:430	Mutation altering degron motif	0.8102
p.M423L	TCGA-FS-A4F5	SKCM	TCGA	SLR	DEG_APCC_TPR_1	428:430	Mutation rewiring degron network	0.1944
p.M423L	DO37881	SKCM	ICGC	SLR	DEG_APCC_TPR_1	428:430	Mutation rewiring degron network	0.1944
p.M423R	DO228125	EOPC	ICGC	SLR	DEG_APCC_TPR_1	428:430	Mutation rewiring degron network	0.1944
p.G421E	DO229465	SKCA	ICGC	SLR	DEG_APCC_TPR_1	428:430	Mutation rewiring degron network	0.1389

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*NOTE: the Kaplan plots were collected from OncoLnc