DegronMD - Q9BXK5(BCL2L13)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.K16N	TCGA-06-5416	GBM	TCGA	ASSST	DEG_SPOP_SBC_1	2:6	Mutation substituting flanking lysine	0.1667
p.K16N	DO10880	GBM	ICGC	ASSST	DEG_SPOP_SBC_1	2:6	Mutation substituting flanking lysine	0.1667
p.A2V	TCGA-62-A46P	LUAD	TCGA	ASSST	DEG_SPOP_SBC_1	2:6	Mutation altering degron motif	0.5825
p.A2V	DO25767	LUAD	ICGC	ASSST	DEG_SPOP_SBC_1	2:6	Mutation altering degron motif	0.5825
p.A2V	SIDM02050	Colorectal Carcinoma	GDSC	ASSST	DEG_SPOP_SBC_1	2:6	Mutation altering degron motif	0.5825
p.E14K	TCGA-AC-A23H	BRCA	TCGA	ASSST	DEG_SPOP_SBC_1	2:6	Mutation rewiring degron network	0.1111
p.E14K	DO2401	BRCA	ICGC	ASSST	DEG_SPOP_SBC_1	2:6	Mutation rewiring degron network	0.1111
p.S4C	TCGA-IR-A3LI	CESC	TCGA	ASSST	DEG_SPOP_SBC_1	2:6	Mutation altering degron motif	0.8652
p.S4C	DO44400	CESC	ICGC	ASSST	DEG_SPOP_SBC_1	2:6	Mutation altering degron motif	0.8652
p.S14Y	DO37405	SKCM	ICGC	ASSST	DEG_SPOP_SBC_1	2:6	Mutation rewiring degron network	0.1111

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons