DegronMD - Q9BZC7(ABCA2)

ABCA2

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.G1387V	TCGA-85-6561	LUSC	TCGA	DYR	CBL_MET	1395:1397	Mutation rewiring degron network	0.1111
p.R1398C	TCGA-HF-A5NB	STAD	TCGA	DYR	CBL_MET	1395:1397	Mutation rewiring degron network	0.3056
p.D1405E	DO229019	LICA	ICGC	DYR	CBL_MET	1395:1397	Mutation rewiring degron network	0.1111
p.G1386V	DO26518	LUSC	ICGC	DYR	CBL_MET	1395:1397	Mutation rewiring degron network	0.0833
p.P1403S	DO222390	MELA	ICGC	DYR	CBL_MET	1395:1397	Mutation rewiring degron network	0.1667
p.R1397C	DO50127	STAD	ICGC	DYR	CBL_MET	1395:1397	Mutation altering degron motif	0.8301
p.A1387V	DO229234	THCA	ICGC	DYR	CBL_MET	1395:1397	Mutation rewiring degron network	0.1111
p.D1385N	SIDM00278	Esophageal Squamous Cell Carcinoma	GDSC	DYR	CBL_MET	1395:1397	Mutation rewiring degron network	0.0556
p.D1385N	ACH-000305	Esophageal Cancer	CCLE	DYR	CBL_MET	1395:1397	Mutation rewiring degron network	0.0556
p.D1385N	EC-GI-10	oesophagus	COSMIC	DYR	CBL_MET	1395:1397	Mutation rewiring degron network	0.0556
p.V1393I	SIDM01575	Plasma Cell Myeloma	GDSC	DYR	CBL_MET	1395:1397	Mutation blocking phosphorylation signal	0.7222
p.D1392G	ACH-000937	Leukemia	CCLE	DYR	CBL_MET	1395:1397	Mutation rewiring degron network	0.25
p.N1403T	ACH-001991	Primary	CCLE	DYR	CBL_MET	1395:1397	Mutation rewiring degron network	0.1667
p.A1388V	ACH-002026	Endometrial/Uterine Cancer	CCLE	DYR	CBL_MET	1395:1397	Mutation rewiring degron network	0.1389
p.S1402L	HCC2218	breast	COSMIC	DYR	CBL_MET	1395:1397	Mutation rewiring degron network	0.1944

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*NOTE: the Kaplan plots were collected from OncoLnc