DegronMD - Q9BZD6(PRRG4)

PRRG4

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.P206S	TCGA-06-2564	GBM	TCGA	PPPY	ITCH	204:207	Mutation altering degron motif	0.5641
p.P206S	DO13378	GBM	ICGC	PPPY	ITCH	204:207	Mutation altering degron motif	0.5641
p.R215M	TCGA-37-3792	LUSC	TCGA	PPPY	ITCH	204:207	Mutation rewiring degron network	0.1111
p.R215M	DO27192	LUSC	ICGC	PPPY	ITCH	204:207	Mutation rewiring degron network	0.1111
p.A194V	TCGA-AG-A036	READ	TCGA	PPPY	ITCH	204:207	Mutation rewiring degron network	0.0556
p.A194V	TCGA-EO-A22U	UCEC	TCGA	PPPY	ITCH	204:207	Mutation rewiring degron network	0.0556
p.A194V	TCGA-FI-A2D5	UCEC	TCGA	PPPY	ITCH	204:207	Mutation rewiring degron network	0.0556
p.A194V	DO37245	READ	ICGC	PPPY	ITCH	204:207	Mutation rewiring degron network	0.0556
p.A194V	DO43755	UCEC	ICGC	PPPY	ITCH	204:207	Mutation rewiring degron network	0.0556
p.A194V	DO41331	UCEC	ICGC	PPPY	ITCH	204:207	Mutation rewiring degron network	0.0556
p.F214L	DO222884	COCA	ICGC	PPPY	ITCH	204:207	Mutation rewiring degron network	0.1389
p.Y207C	SIDM01394	Kidney Carcinoma	GDSC	PPPY	ITCH	204:207	Mutation altering degron motif	0.8198
p.Y207C	ACH-000907	Kidney Cancer	CCLE	PPPY	ITCH	204:207	Mutation altering degron motif	0.8198

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*NOTE: the Kaplan plots were collected from OncoLnc