DegronMD - Q9BZY9(TRIM31)

TRIM31

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.S347L	TCGA-D3-A8GI	SKCM	TCGA	PGSSS	DEG_SPOP_SBC_1	336:340	Mutation rewiring degron network	0.1389
p.S347L	DO50284	SKCM	ICGC	PGSSS	DEG_SPOP_SBC_1	336:340	Mutation rewiring degron network	0.1389
p.G337R	TCGA-EO-A22R	UCEC	TCGA	PGSSS	DEG_SPOP_SBC_1	336:340	Mutation altering degron motif	0.6457
p.G337R	DO42713	UCEC	ICGC	PGSSS	DEG_SPOP_SBC_1	336:340	Mutation altering degron motif	0.6457
p.G348R	TCGA-FD-A3N5	BLCA	TCGA	PGSSS	DEG_SPOP_SBC_1	336:340	Mutation rewiring degron network	0.1111
p.G348R	DO639	BLCA	ICGC	PGSSS	DEG_SPOP_SBC_1	336:340	Mutation rewiring degron network	0.1111
p.H328Y	TCGA-Q9-A6FW	ESCA	TCGA	PGSSS	DEG_SPOP_SBC_1	336:340	Mutation rewiring degron network	0.1111
p.S340C	TCGA-XF-AAN5	BLCA	TCGA	PGSSS	DEG_SPOP_SBC_1	336:340	Mutation altering degron motif	0.8652
p.S340C	DO51945	BLCA	ICGC	PGSSS	DEG_SPOP_SBC_1	336:340	Mutation altering degron motif	0.8652
p.K329N	DO222884	COCA	ICGC	PGSSS	DEG_SPOP_SBC_1	336:340	Mutation substituting flanking lysine	0.25
p.T346I	DO50780	LIRI	ICGC	PGSSS	DEG_SPOP_SBC_1	336:340	Mutation rewiring degron network	0.1667
p.G337W	DO51149	PRAD	ICGC	PGSSS	DEG_SPOP_SBC_1	336:340	Mutation altering degron motif	0.6714

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*NOTE: the Kaplan plots were collected from OncoLnc