DegronMD - Q9H0I2(ENKD1)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.R114H	TCGA-3M-AB46	STAD	TCGA	EKENL	DEG_APCC_KENBOX_2	101:105	Mutation rewiring degron network	0.0833
p.R114H	DO222326	STAD	ICGC	EKENL	DEG_APCC_KENBOX_2	101:105	Mutation rewiring degron network	0.0833
p.K98N	TCGA-AA-3966	COAD	TCGA	EKENL	DEG_APCC_KENBOX_2	101:105	Mutation substituting flanking lysine	0.3611
p.K98N	DO10068	COAD	ICGC	EKENL	DEG_APCC_KENBOX_2	101:105	Mutation substituting flanking lysine	0.3611
p.R114C	TCGA-AX-A06F	UCEC	TCGA	EKENL	DEG_APCC_KENBOX_2	101:105	Mutation rewiring degron network	0.0833
p.R114C	DO41752	UCEC	ICGC	EKENL	DEG_APCC_KENBOX_2	101:105	Mutation rewiring degron network	0.0833
p.R107L	TCGA-D7-A6EY	STAD	TCGA	EKENL	DEG_APCC_KENBOX_2	101:105	Mutation rewiring degron network	0.2778
p.R107L	DO50118	STAD	ICGC	EKENL	DEG_APCC_KENBOX_2	101:105	Mutation rewiring degron network	0.2778
p.D96E	DO229028	LICA	ICGC	EKENL	DEG_APCC_KENBOX_2	101:105	Mutation rewiring degron network	0.1944

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons