DegronMD - Q9H0R4(HDHD2)

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GO - Molecular function (MF): View more >>

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.P248H	TCGA-EE-A2MM	SKCM	TCGA	PPPY	ITCH	238:241	Mutation rewiring degron network	0.1389
p.P248H	DO37770	SKCM	ICGC	PPPY	ITCH	238:241	Mutation rewiring degron network	0.1389
p.P240L	DO222420	MELA	ICGC	PPPY	ITCH	238:241	Mutation altering degron motif	0.6471
p.D232Y	DO232224	PBCA	ICGC	PPPY	ITCH	238:241	Mutation rewiring degron network	0.1667
p.P240S	SIDM00392	Melanoma	GDSC	PPPY	ITCH	238:241	Mutation altering degron motif	0.5641
p.P240S	ACH-000810	Skin Cancer	CCLE	PPPY	ITCH	238:241	Mutation altering degron motif	0.5641
p.P240S	SK-MEL-30	skin	COSMIC	PPPY	ITCH	238:241	Mutation altering degron motif	0.5641

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons