DegronMD - Q9H116(GZF1)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.G253C	TCGA-55-7911	LUAD	TCGA	DYR	CBL_MET	257:259	Mutation rewiring degron network	0.2222
p.G253C	DO24821	LUAD	ICGC	DYR	CBL_MET	257:259	Mutation rewiring degron network	0.2222
p.G256V	TCGA-DJ-A2QB	THCA	TCGA	DYR	CBL_MET	257:259	Mutation rewiring degron network	0.3056
p.G256V	DO39421	THCA	ICGC	DYR	CBL_MET	257:259	Mutation rewiring degron network	0.3056
p.P266L	TCGA-EO-A22U	UCEC	TCGA	DYR	CBL_MET	257:259	Mutation rewiring degron network	0.1389
p.P266L	DO43755	UCEC	ICGC	DYR	CBL_MET	257:259	Mutation rewiring degron network	0.1389
p.P266L	SIDM01012	Other Blood Cancers	GDSC	DYR	CBL_MET	257:259	Mutation rewiring degron network	0.1389
p.P266L	ACH-000346	Leukemia	CCLE	DYR	CBL_MET	257:259	Mutation rewiring degron network	0.1389
p.P266L	JVM-3	haematopoietic and lymphoid tissue	COSMIC	DYR	CBL_MET	257:259	Mutation rewiring degron network	0.1389
p.R259M	TCGA-EO-A3B0	UCEC	TCGA	DYR	CBL_MET	257:259	Mutation altering degron motif	0.8632
p.R259M	DO219773	UCEC	ICGC	DYR	CBL_MET	257:259	Mutation altering degron motif	0.8632
p.E252K	DO48409	BLCA	ICGC	DYR	CBL_MET	257:259	Mutation rewiring degron network	0.1944
p.P261H	DO233737	GACA	ICGC	DYR	CBL_MET	257:259	Mutation rewiring degron network	0.2778
p.P261L	DO23146	LINC	ICGC	DYR	CBL_MET	257:259	Mutation rewiring degron network	0.2778
p.P261L	DO45071	LINC	ICGC	DYR	CBL_MET	257:259	Mutation rewiring degron network	0.2778
p.Y258C	SIDM01007	T-Lymphoblastic Leukemia	GDSC	DYR	CBL_MET	257:259	Mutation altering degron motif	0.7087
p.Y258C	ACH-002256	Leukemia	CCLE	DYR	CBL_MET	257:259	Mutation altering degron motif	0.7087
p.Y258C	KARPAS-45	haematopoietic and lymphoid tissue	COSMIC	DYR	CBL_MET	257:259	Mutation altering degron motif	0.7087

Kaplan plot for GZF1 in

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons

GZF1

UniProt ID: Q9H116

Entrez ID: 64412

Protein name: GDNF-inducible zinc finger protein 1 (Zinc finger and BTB domain-containing protein 23) (Zinc finger protein 336)

External links: UniprotKB HGNC RefSeq COSMIC

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Kaplan plot for GZF1 in