DegronMD - Q9H2F5(EPC1)

GO - Biological processes (BP): View more >>

GO - Molecular function (MF): View more >>

GO - Cellular component (CC): View more >>

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.A792V	TCGA-AP-A051	UCEC	TCGA	VPSSS	DEG_SPOP_SBC_1	802:806	Mutation rewiring degron network	0.0556
p.P803Q	TCGA-EE-A2GN	SKCM	TCGA	VPSSS	DEG_SPOP_SBC_1	802:806	Mutation altering degron motif	0.5924
p.S800F	TCGA-FS-A4F8	SKCM	TCGA	VPSSS	DEG_SPOP_SBC_1	802:806	Mutation rewiring degron network	0.2778
p.R813S	TCGA-GN-A262	SKCM	TCGA	VPSSS	DEG_SPOP_SBC_1	802:806	Mutation rewiring degron network	0.1389
p.S807Y	TCGA-IB-7651	PAAD	TCGA	VPSSS	DEG_SPOP_SBC_1	802:806	Mutation rewiring degron network	0.3056
p.R813G	TCGA-VQ-A8P2	STAD	TCGA	VPSSS	DEG_SPOP_SBC_1	802:806	Mutation rewiring degron network	0.1389
p.A795V	SIDM00683	Prostate Carcinoma	GDSC	VPSSS	DEG_SPOP_SBC_1	802:806	Mutation rewiring degron network	0.1389
p.A795V	LNCaP-Clone-FGC	prostate	COSMIC	VPSSS	DEG_SPOP_SBC_1	802:806	Mutation rewiring degron network	0.1389
p.P812L	SIDM01175	Other Sarcomas	GDSC	VPSSS	DEG_SPOP_SBC_1	802:806	Mutation rewiring degron network	0.1667
p.P812L	SW684	soft tissue	COSMIC	VPSSS	DEG_SPOP_SBC_1	802:806	Mutation rewiring degron network	0.1667
p.A804V	ACH-000959	Colon/Colorectal Cancer	CCLE	VPSSS	DEG_SPOP_SBC_1	802:806	Mutation altering degron motif	0.6936
p.E811G	ACH-000978	Endometrial/Uterine Cancer	CCLE	VPSSS	DEG_SPOP_SBC_1	802:806	Mutation rewiring degron network	0.1944
p.E811G	EN	endometrium	COSMIC	VPSSS	DEG_SPOP_SBC_1	802:806	Mutation rewiring degron network	0.1944

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons