DegronMD - Q9H3R2(MUC13)

GO - Biological processes (BP): View more >>

GO - Molecular function (MF): View more >>

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.A34V	TCGA-2W-A8YY	CESC	TCGA	AVTTT	DEG_SPOP_SBC_1	27:31	Mutation rewiring degron network	0.25
p.A34V	DO223732	CESC	ICGC	AVTTT	DEG_SPOP_SBC_1	27:31	Mutation rewiring degron network	0.25
p.T30S	TCGA-AJ-A5DW	UCEC	TCGA	AVTTT	DEG_SPOP_SBC_1	27:31	Mutation altering degron motif	0.6005
p.T30S	DO50075	UCEC	ICGC	AVTTT	DEG_SPOP_SBC_1	27:31	Mutation altering degron motif	0.6005
p.P38H	TCGA-EI-6882	READ	TCGA	AVTTT	DEG_SPOP_SBC_1	27:31	Mutation rewiring degron network	0.1389
p.P38H	DO36531	READ	ICGC	AVTTT	DEG_SPOP_SBC_1	27:31	Mutation rewiring degron network	0.1389
p.A18V	DO228947	LICA	ICGC	AVTTT	DEG_SPOP_SBC_1	27:31	Mutation rewiring degron network	0.0833
p.N20K	DO229037	LICA	ICGC	AVTTT	DEG_SPOP_SBC_1	27:31	Mutation rewiring degron network	0.1389
p.A34E	DO50713	ORCA	ICGC	AVTTT	DEG_SPOP_SBC_1	27:31	Mutation rewiring degron network	0.25
p.P38S	DO229456	SKCA	ICGC	AVTTT	DEG_SPOP_SBC_1	27:31	Mutation rewiring degron network	0.1389
p.A18S	SIDM02049	Pancreatic Carcinoma	GDSC	AVTTT	DEG_SPOP_SBC_1	27:31	Mutation rewiring degron network	0.0833

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons