DegronMD - Q9H4A9(DPEP2)

GO - Biological processes (BP): View more >>

GO - Molecular function (MF): View more >>

GO - Cellular component (CC): View more >>

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.P49S	TCGA-EB-A6QY	SKCM	TCGA	APSTT	DEG_SPOP_SBC_1	59:63	Mutation rewiring degron network	0.0556
p.P49S	DO222434	MELA	ICGC	APSTT	DEG_SPOP_SBC_1	59:63	Mutation rewiring degron network	0.0556
p.P49S	DO48702	SKCM	ICGC	APSTT	DEG_SPOP_SBC_1	59:63	Mutation rewiring degron network	0.0556
p.P60R	DO48374	BLCA	ICGC	APSTT	DEG_SPOP_SBC_1	59:63	Mutation altering degron motif	0.6401
p.L64I	DO229034	LICA	ICGC	APSTT	DEG_SPOP_SBC_1	59:63	Mutation rewiring degron network	0.3056
p.G56D	ACH-000776	Brain Cancer	CCLE	APSTT	DEG_SPOP_SBC_1	59:63	Mutation rewiring degron network	0.25
p.H52N	ACH-000969	Colon/Colorectal Cancer	CCLE	APSTT	DEG_SPOP_SBC_1	59:63	Mutation rewiring degron network	0.1389

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons