DegronMD - Q9HAD4(WDR41)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.R47Q	TCGA-AA-A00N	COAD	TCGA	DYR	CBL_MET	54:56	Mutation rewiring degron network	0.1389
p.R47Q	DO9876	COAD	ICGC	DYR	CBL_MET	54:56	Mutation rewiring degron network	0.1389
p.D54Y	TCGA-XF-AAMG	BLCA	TCGA	DYR	CBL_MET	54:56	Mutation altering degron motif	0.7325
p.D54Y	DO219049	BLCA	ICGC	DYR	CBL_MET	54:56	Mutation altering degron motif	0.7325
p.I45S	DO222884	COCA	ICGC	DYR	CBL_MET	54:56	Mutation rewiring degron network	0.0833
p.V60A	DO52098	HNSC	ICGC	DYR	CBL_MET	54:56	Mutation rewiring degron network	0.2222
p.R58I	DO46657	PAAD	ICGC	DYR	CBL_MET	54:56	Mutation rewiring degron network	0.2778
p.R58I	DO41903	UCEC	ICGC	DYR	CBL_MET	54:56	Mutation rewiring degron network	0.2778
p.I61V	DO232761	PBCA	ICGC	DYR	CBL_MET	54:56	Mutation rewiring degron network	0.1944
p.T59I	ARH-77	haematopoietic and lymphoid tissue	COSMIC	DYR	CBL_MET	54:56	Mutation rewiring degron network	0.25

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons