DegronMD - Q9HC44(GPBP1L1)

GO - Biological processes (BP): View more >>

GO - Molecular function (MF): View more >>

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.S307G	TCGA-DU-6392	LGG	TCGA	PSSTT	DEG_SPOP_SBC_1	297:301	Mutation rewiring degron network	0.1667
p.S307G	DO22237	LGG	ICGC	PSSTT	DEG_SPOP_SBC_1	297:301	Mutation rewiring degron network	0.1667
p.S292Y	TCGA-EO-A22R	UCEC	TCGA	PSSTT	DEG_SPOP_SBC_1	297:301	Mutation blocking phosphorylation signal	0.6389
p.S292Y	DO42713	UCEC	ICGC	PSSTT	DEG_SPOP_SBC_1	297:301	Mutation blocking phosphorylation signal	0.6389
p.I304V	TCGA-GR-A4D6	DLBC	TCGA	PSSTT	DEG_SPOP_SBC_1	297:301	Mutation rewiring degron network	0.25
p.I304V	DO219909	DLBC	ICGC	PSSTT	DEG_SPOP_SBC_1	297:301	Mutation rewiring degron network	0.25
p.A288E	DO229029	LICA	ICGC	PSSTT	DEG_SPOP_SBC_1	297:301	Mutation rewiring degron network	0.0833
p.S292F	DO231043	LUSC	ICGC	PSSTT	DEG_SPOP_SBC_1	297:301	Mutation blocking phosphorylation signal	0.6389

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons