DegronMD - Q9HCQ5(GALNT9)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.S132N	TCGA-2W-A8YY	CESC	TCGA	DYR	CBL_MET	135:137	Mutation rewiring degron network	0.25
p.S132N	DO223732	CESC	ICGC	DYR	CBL_MET	135:137	Mutation rewiring degron network	0.25
p.A147T	TCGA-A5-A0VP	UCEC	TCGA	DYR	CBL_MET	135:137	Mutation rewiring degron network	0.0556
p.A147T	DO42600	UCEC	ICGC	DYR	CBL_MET	135:137	Mutation rewiring degron network	0.0556
p.R126C	TCGA-A6-5665	COAD	TCGA	DYR	CBL_MET	135:137	Mutation rewiring degron network	0.0833
p.R126C	DO9756	COAD	ICGC	DYR	CBL_MET	135:137	Mutation rewiring degron network	0.0833
p.R136Q	TCGA-AD-6965	COAD	TCGA	DYR	CBL_MET	135:137	Mutation altering degron motif	0.7329
p.R136Q	DO9018	COAD	ICGC	DYR	CBL_MET	135:137	Mutation altering degron motif	0.7329
p.R131L	TCGA-AK-3436	KIRC	TCGA	DYR	CBL_MET	135:137	Mutation rewiring degron network	0.2222
p.R131L	DO20239	KIRC	ICGC	DYR	CBL_MET	135:137	Mutation rewiring degron network	0.2222
p.R137W	TCGA-CK-5913	COAD	TCGA	DYR	CBL_MET	135:137	Mutation altering degron motif	0.8634
p.R137W	DO8826	COAD	ICGC	DYR	CBL_MET	135:137	Mutation altering degron motif	0.8634
p.S138I	TCGA-E5-A2PC	BLCA	TCGA	DYR	CBL_MET	135:137	Mutation rewiring degron network	0.3056
p.S138I	DO702	BLCA	ICGC	DYR	CBL_MET	135:137	Mutation rewiring degron network	0.3056
p.G146W	TCGA-GN-A264	SKCM	TCGA	DYR	CBL_MET	135:137	Mutation rewiring degron network	0.0833
p.G146W	DO37527	SKCM	ICGC	DYR	CBL_MET	135:137	Mutation rewiring degron network	0.0833
p.R136W	TCGA-HU-A4G3	STAD	TCGA	DYR	CBL_MET	135:137	Mutation altering degron motif	0.8634
p.R136W	DO47807	STAD	ICGC	DYR	CBL_MET	135:137	Mutation altering degron motif	0.8634
p.C127S	TCGA-L5-A4OW	ESCA	TCGA	DYR	CBL_MET	135:137	Mutation rewiring degron network	0.1111
p.R131Q	TCGA-QQ-A8VF	SARC	TCGA	DYR	CBL_MET	135:137	Mutation rewiring degron network	0.2222
p.R131Q	DO49460	PACA	ICGC	DYR	CBL_MET	135:137	Mutation rewiring degron network	0.2222
p.R131Q	DO220258	SARC	ICGC	DYR	CBL_MET	135:137	Mutation rewiring degron network	0.2222
p.R131H	DO8634	COAD	ICGC	DYR	CBL_MET	135:137	Mutation rewiring degron network	0.2222
p.R131H	DO52513	EOPC	ICGC	DYR	CBL_MET	135:137	Mutation rewiring degron network	0.2222
p.R146H	DO52450	COCA	ICGC	DYR	CBL_MET	135:137	Mutation rewiring degron network	0.0833
p.R146H	DO11388	GBM	ICGC	DYR	CBL_MET	135:137	Mutation rewiring degron network	0.0833
p.A139T	HuP-T4	pancreas	COSMIC	DYR	CBL_MET	135:137	Mutation rewiring degron network	0.2778

Kaplan plot for GALNT9 in

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons

GALNT9

UniProt ID: Q9HCQ5

Entrez ID: 50614

Protein name: Polypeptide N-acetylgalactosaminyltransferase 9 (EC 2.4.1.41) (Polypeptide GalNAc transferase 9) (GalNAc-T9) (pp-GaNTase 9) (Protein-UDP acetylgalactosaminyltransferase 9) (UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 9)

External links: UniprotKB HGNC RefSeq COSMIC

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Kaplan plot for GALNT9 in