DegronMD - Q9NP87(POLM)

POLM

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.D16N	TCGA-MV-A51V	BLCA	TCGA	AASST	DEG_SPOP_SBC_1	17:21	Mutation rewiring degron network	0.3056
p.D16N	DO474	BLCA	ICGC	AASST	DEG_SPOP_SBC_1	17:21	Mutation rewiring degron network	0.3056
p.D16N	DO50810	LICA	ICGC	AASST	DEG_SPOP_SBC_1	17:21	Mutation rewiring degron network	0.3056
p.D16N	DO26599	LUSC	ICGC	AASST	DEG_SPOP_SBC_1	17:21	Mutation rewiring degron network	0.3056
p.D16N	ACH-000490	Cervical Cancer	CCLE	AASST	DEG_SPOP_SBC_1	17:21	Mutation rewiring degron network	0.3056
p.S19Y	DO223045	ESCA	ICGC	AASST	DEG_SPOP_SBC_1	17:21	Mutation altering degron motif	0.8231
p.D16Y	DO232838	NACA	ICGC	AASST	DEG_SPOP_SBC_1	17:21	Mutation rewiring degron network	0.3056
p.D16Y	ACH-000951	Lung Cancer	CCLE	AASST	DEG_SPOP_SBC_1	17:21	Mutation rewiring degron network	0.3056
p.G11R	DO229191	THCA	ICGC	AASST	DEG_SPOP_SBC_1	17:21	Mutation rewiring degron network	0.1667
p.T21K	DO229211	THCA	ICGC	AASST	DEG_SPOP_SBC_1	17:21	Mutation altering degron motif	0.8417
p.P23L	SIDM00548	Squamous Cell Lung Carcinoma	GDSC	AASST	DEG_SPOP_SBC_1	17:21	Mutation rewiring degron network	0.2778
p.P23L	SIDM01031	Esophageal Squamous Cell Carcinoma	GDSC	AASST	DEG_SPOP_SBC_1	17:21	Mutation rewiring degron network	0.2778
p.P23L	SIDM00192	Colorectal Carcinoma	GDSC	AASST	DEG_SPOP_SBC_1	17:21	Mutation rewiring degron network	0.2778

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*NOTE: the Kaplan plots were collected from OncoLnc