DegronMD - Q9NQR7(CCDC177)

CCDC177

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.A250T	DO6898	CLLE	ICGC	ASSSS	DEG_SPOP_SBC_1	250:254	Mutation altering degron motif	0.7139
p.A250T	SIDM01314	Colorectal Carcinoma	GDSC	ASSSS	DEG_SPOP_SBC_1	250:254	Mutation altering degron motif	0.7139
p.L244I	DO26769	LUSC	ICGC	ASSSS	DEG_SPOP_SBC_1	250:254	Mutation rewiring degron network	0.1667
p.S279L	DO36881	READ	ICGC	ASSTT	DEG_SPOP_SBC_1	280:284	Mutation rewiring degron network	0.3056
p.A198T	DO229479	SKCA	ICGC	AGSSS	DEG_SPOP_SBC_1	185:189	Mutation rewiring degron network	0.0833
p.A177D	DO218852	SKCA	ICGC	AGSSS	DEG_SPOP_SBC_1	185:189	Mutation rewiring degron network	0.1111
p.A176G	DO218852	SKCA	ICGC	AGSSS	DEG_SPOP_SBC_1	185:189	Mutation rewiring degron network	0.0833
p.A277T	SIDM02059	Colorectal Carcinoma	GDSC	ASSTT	DEG_SPOP_SBC_1	280:284	Mutation rewiring degron network	0.25
p.G278V	ACH-000581	Gastric Cancer	CCLE	ASSTT	DEG_SPOP_SBC_1	280:284	Mutation rewiring degron network	0.2778
p.S282P	ACH-000982	Colon/Colorectal Cancer	CCLE	ASSTT	DEG_SPOP_SBC_1	280:284	Mutation altering degron motif	0.6752

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*NOTE: the Kaplan plots were collected from OncoLnc