DegronMD - Q9P0J1(PDP1)

PDP1

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.R392T	TCGA-39-5031	LUSC	TCGA	PPNY	ITCH	386:389	Mutation rewiring degron network	0.25
p.K391N	TCGA-AJ-A3QS	UCEC	TCGA	PPNY	ITCH	386:389	Mutation rewiring degron network	0.2778
p.K391N	TCGA-EK-A2RJ	CESC	TCGA	PPNY	ITCH	386:389	Mutation rewiring degron network	0.2778
p.D380G	TCGA-W3-AA1V	SKCM	TCGA	PPNY	ITCH	386:389	Mutation rewiring degron network	0.1667
p.P393S	DO21679	LAML	ICGC	PPNY	ITCH	386:389	Mutation rewiring degron network	0.2222
p.P386S	DO219878	SKCA	ICGC	PPNY	ITCH	386:389	Mutation altering degron motif	0.6752
p.P393L	DO37432	SKCM	ICGC	PPNY	ITCH	386:389	Mutation rewiring degron network	0.2222
p.N377H	DO42793	UCEC	ICGC	PPNY	ITCH	386:389	Mutation rewiring degron network	0.0833
p.L389V	SIDM00539	Esophageal Carcinoma	GDSC	PPNY	ITCH	386:389	Mutation altering degron motif	0.6765
p.L389V	ESO26	oesophagus	COSMIC	PPNY	ITCH	386:389	Mutation altering degron motif	0.6765
p.N379D	ACH-000971	Colon/Colorectal Cancer	CCLE	PPNY	ITCH	386:389	Mutation rewiring degron network	0.1389
p.N379D	HCT-116	large intestine	COSMIC	PPNY	ITCH	386:389	Mutation rewiring degron network	0.1389
p.N377S	ACH-001075	Lung Cancer	CCLE	PPNY	ITCH	386:389	Mutation rewiring degron network	0.0833
p.N377S	NCI-H292	lung	COSMIC	PPNY	ITCH	386:389	Mutation rewiring degron network	0.0833

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*NOTE: the Kaplan plots were collected from OncoLnc