DegronMD - Q9P0K8(FOXJ2)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.F241L	TCGA-AN-A046	BRCA	TCGA	PPLY	ITCH	230:233	Mutation rewiring degron network	0.1111
p.F241L	TCGA-AX-A05Z	UCEC	TCGA	PPLY	ITCH	230:233	Mutation rewiring degron network	0.1111
p.F241L	TCGA-AX-A2HC	UCEC	TCGA	PPLY	ITCH	230:233	Mutation rewiring degron network	0.1111
p.F241L	TCGA-DK-A6AW	BLCA	TCGA	PPLY	ITCH	230:233	Mutation rewiring degron network	0.1111
p.F241L	DO48566	BLCA	ICGC	PPLY	ITCH	230:233	Mutation rewiring degron network	0.1111
p.F241L	DO1285	BRCA	ICGC	PPLY	ITCH	230:233	Mutation rewiring degron network	0.1111
p.F241L	DO36556	READ	ICGC	PPLY	ITCH	230:233	Mutation rewiring degron network	0.1111
p.F241L	DO40884	UCEC	ICGC	PPLY	ITCH	230:233	Mutation rewiring degron network	0.1111
p.F241L	DO41572	UCEC	ICGC	PPLY	ITCH	230:233	Mutation rewiring degron network	0.1111
p.P231H	TCGA-B5-A11E	UCEC	TCGA	PPLY	ITCH	230:233	Mutation altering degron motif	0.7694
p.P231H	DO41644	UCEC	ICGC	PPLY	ITCH	230:233	Mutation altering degron motif	0.7694
p.Y233C	TCGA-CV-A6JE	HNSC	TCGA	PPLY	ITCH	230:233	Mutation altering degron motif	0.7087
p.Y233C	DO49046	HNSC	ICGC	PPLY	ITCH	230:233	Mutation altering degron motif	0.7087
p.K240E	TCGA-K4-AAQO	BLCA	TCGA	PPLY	ITCH	230:233	Mutation substituting flanking lysine	0.25
p.K240E	DO219030	BLCA	ICGC	PPLY	ITCH	230:233	Mutation substituting flanking lysine	0.25
p.D238G	DO230334	COCA	ICGC	PPLY	ITCH	230:233	Mutation rewiring degron network	0.1944
p.D238G	SIDM01667	B-Cell Non-Hodgkin's Lymphoma	GDSC	PPLY	ITCH	230:233	Mutation rewiring degron network	0.1944
p.P230S	DO219878	SKCA	ICGC	PPLY	ITCH	230:233	Mutation altering degron motif	0.6752
p.A220T	SIDM00661	B-Cell Non-Hodgkin's Lymphoma	GDSC	PPLY	ITCH	230:233	Mutation rewiring degron network	0.0556
p.A220T	ACH-000914	Lymphoma	CCLE	PPLY	ITCH	230:233	Mutation rewiring degron network	0.0556
p.A220T	HT	haematopoietic and lymphoid tissue	COSMIC	PPLY	ITCH	230:233	Mutation rewiring degron network	0.0556
p.S225N	SIDM01451	Pancreatic Carcinoma	GDSC	PPLY	ITCH	230:233	Mutation rewiring degron network	0.1944
p.S225N	ACH-000933	Pancreatic Cancer	CCLE	PPLY	ITCH	230:233	Mutation rewiring degron network	0.1944

Kaplan plot for FOXJ2 in

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons

FOXJ2

UniProt ID: Q9P0K8

Entrez ID: 55810

Protein name: Forkhead box protein J2 (Fork head homologous X)

External links: UniprotKB HGNC RefSeq COSMIC

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Kaplan plot for FOXJ2 in