DegronMD: protein-targeted degradation, mutation and drug response to degrons
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BSML
CPH
CGC
CFAP97
UniProt ID:
Q9P2B7
Entrez ID:
57587
Protein name:
Cilia- and flagella-associated protein 97
External links:
UniprotKB
HGNC
RefSeq
COSMIC
Please click
HERE
for better display.
Functional annotation
Mutations
Degrons
Degron mutations
Network-rewiring
Drug response
Drug resistance
...
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GO - Biological processes (BP):
spermatogenesis [GO:0007283]...
spermatogenesis [GO:0007283]
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GO - Molecular function (MF):
...
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GO - Cellular component (CC):
...
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Choose a PDB ID:
Open in full screen with detailed sequence annotations
CFAP97
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AAchange
Cancer
Sample
Mutation type
Dataset
Degron hit
Class
E3 ligase
Source protein
Location
Detail
Mutation
Sample
Cancer
Degron hit
Class
Location
Dataset
Mutation
Sample
Cancer
Dataset
Degron hit
Class
Location
Type
Impact score
p.I162T
SIDM00654
Small Cell Lung Carcinoma
GDSC
VSSSS
DEG_SPOP_SBC_1
169:173
Mutation rewiring degron network
0.1389
p.I162T
SIDM00849
Kidney Carcinoma
GDSC
VSSSS
DEG_SPOP_SBC_1
169:173
Mutation rewiring degron network
0.1389
p.I162T
SIDM00793
Burkitt's Lymphoma
GDSC
VSSSS
DEG_SPOP_SBC_1
169:173
Mutation rewiring degron network
0.1389
Cell ID
Cell name
Cancer
Drug
IC50(uM)
Dataset
Protein
Degron
Cancer code
Cancer type
Drug
AVG_IC50(uM)(mutated)
AVG_IC50(uM)(Non-mutated)
Details
Kaplan plot for CFAP97 in
Select cancer type:
Download patient class data (Lower:Upper = 50%:50%)
*NOTE: the Kaplan plots were collected from
OncoLnc