DegronMD - Q9P2C4(TMEM181)

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GO - Cellular component (CC): View more >>

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.P56H	TCGA-A5-A0G1	UCEC	TCGA	PLTTS	DEG_SPOP_SBC_1	47:51	Mutation rewiring degron network	0.1944
p.P56H	DO42472	UCEC	ICGC	PLTTS	DEG_SPOP_SBC_1	47:51	Mutation rewiring degron network	0.1944
p.R46C	DO233168	GACA	ICGC	PLTTS	DEG_SPOP_SBC_1	47:51	Mutation rewiring degron network	0.3056
p.A32S	DO229019	LICA	ICGC	AVSSS	DEG_SPOP_SBC_1	25:29	Mutation rewiring degron network	0.25
p.A55S	DO229038	LICA	ICGC	PLTTS	DEG_SPOP_SBC_1	47:51	Mutation rewiring degron network	0.2222
p.S43N	DO27484	LUSC	ICGC	PLTTS	DEG_SPOP_SBC_1	47:51	Mutation rewiring degron network	0.2222
p.A45T	DO229229	THCA	ICGC	PLTTS	DEG_SPOP_SBC_1	47:51	Mutation rewiring degron network	0.2778
p.R33S	DO229240	THCA	ICGC	AVSSS	DEG_SPOP_SBC_1	25:29	Mutation rewiring degron network	0.2222
p.P17S	SIDM02015	Colorectal Carcinoma	GDSC	AVSSS	DEG_SPOP_SBC_1	25:29	Mutation rewiring degron network	0.1111

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons