DegronMD - Q9UBN1(CACNG4)

CACNG4

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.R237K	TCGA-B5-A3FA	UCEC	TCGA	ASSSS	DEG_SPOP_SBC_1	224:228	Mutation rewiring degron network	0.0833
p.R237K	DO52402	UCEC	ICGC	ASSSS	DEG_SPOP_SBC_1	224:228	Mutation rewiring degron network	0.0833
p.E220K	TCGA-D9-A6EC	SKCM	TCGA	ASSSS	DEG_SPOP_SBC_1	224:228	Mutation rewiring degron network	0.2222
p.E220K	DO50291	SKCM	ICGC	ASSSS	DEG_SPOP_SBC_1	224:228	Mutation rewiring degron network	0.2222
p.S225F	TCGA-DX-A8BP	SARC	TCGA	ASSSS	DEG_SPOP_SBC_1	224:228	Mutation altering degron motif	0.6871
p.S225F	DO220056	SARC	ICGC	ASSSS	DEG_SPOP_SBC_1	224:228	Mutation altering degron motif	0.6871
p.S227P	TCGA-P3-A5QF	HNSC	TCGA	ASSSS	DEG_SPOP_SBC_1	224:228	Mutation altering degron motif	0.6752
p.S227P	DO44439	HNSC	ICGC	ASSSS	DEG_SPOP_SBC_1	224:228	Mutation altering degron motif	0.6752
p.L222F	DO234379	ESAD	ICGC	ASSSS	DEG_SPOP_SBC_1	224:228	Mutation rewiring degron network	0.2778
p.A224V	SIDM00946	T-Lymphoblastic Leukemia	GDSC	ASSSS	DEG_SPOP_SBC_1	224:228	Mutation altering degron motif	0.5825
p.A224V	ACH-000981	Leukemia	CCLE	ASSSS	DEG_SPOP_SBC_1	224:228	Mutation altering degron motif	0.5825
p.A224V	DND-41	haematopoietic and lymphoid tissue	COSMIC	ASSSS	DEG_SPOP_SBC_1	224:228	Mutation altering degron motif	0.5825

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*NOTE: the Kaplan plots were collected from OncoLnc