DegronMD - Q9UDT6(CLIP2)

CLIP2

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.S318C	TCGA-68-8251	LUSC	TCGA	PSSSS	DEG_SPOP_SBC_1	315:319	Mutation altering degron motif	0.7541
p.S318C	DO26858	LUSC	ICGC	PSSSS	DEG_SPOP_SBC_1	315:319	Mutation altering degron motif	0.7541
p.T312A	TCGA-B5-A3FA	UCEC	TCGA	PSSSS	DEG_SPOP_SBC_1	315:319	Mutation rewiring degron network	0.25
p.T312A	DO52402	UCEC	ICGC	PSSSS	DEG_SPOP_SBC_1	315:319	Mutation rewiring degron network	0.25
p.G307S	TCGA-HT-A615	LGG	TCGA	PSSSS	DEG_SPOP_SBC_1	315:319	Mutation rewiring degron network	0.1111
p.G307S	DO48729	LGG	ICGC	PSSSS	DEG_SPOP_SBC_1	315:319	Mutation rewiring degron network	0.1111
p.S324G	DO233882	GACA	ICGC	PSSSS	DEG_SPOP_SBC_1	315:319	Mutation rewiring degron network	0.1944
p.S318F	DO222875	MELA	ICGC	PSSSS	DEG_SPOP_SBC_1	315:319	Mutation altering degron motif	0.7982
p.V326M	SIDM00572	Gastric Carcinoma	GDSC	PSSSS	DEG_SPOP_SBC_1	315:319	Mutation rewiring degron network	0.1389
p.V326M	ACH-000911	Gastric Cancer	CCLE	PSSSS	DEG_SPOP_SBC_1	315:319	Mutation rewiring degron network	0.1389
p.V326M	NUGC-3	stomach	COSMIC	PSSSS	DEG_SPOP_SBC_1	315:319	Mutation rewiring degron network	0.1389

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*NOTE: the Kaplan plots were collected from OncoLnc