DegronMD - Q9UHA2(SS18L2)

GO - Biological processes (BP): View more >>

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.S73P	TCGA-AX-A2HD	UCEC	TCGA	PTSTS	DEG_SPOP_SBC_1	69:73	Mutation altering degron motif	0.7863
p.S73P	DO42608	UCEC	ICGC	PTSTS	DEG_SPOP_SBC_1	69:73	Mutation altering degron motif	0.7863
p.S68I	DO229019	LICA	ICGC	PTSTS	DEG_SPOP_SBC_1	69:73	Mutation blocking phosphorylation signal	0.75
p.M76I	DO229029	LICA	ICGC	PTSTS	DEG_SPOP_SBC_1	69:73	Mutation rewiring degron network	0.25
p.A65S	DO229034	LICA	ICGC	PTSTS	DEG_SPOP_SBC_1	69:73	Mutation rewiring degron network	0.2222

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons