DegronMD - Q9UID3(VPS51)

VPS51

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.D642Y	TCGA-50-5946	LUAD	TCGA	VYSSS	DEG_SPOP_SBC_1	650:654	Mutation rewiring degron network	0.1111
p.D642Y	DO24556	LUAD	ICGC	VYSSS	DEG_SPOP_SBC_1	650:654	Mutation rewiring degron network	0.1111
p.S663R	TCGA-AP-A059	UCEC	TCGA	VYSSS	DEG_SPOP_SBC_1	650:654	Mutation rewiring degron network	0.0833
p.S663R	DO41361	UCEC	ICGC	VYSSS	DEG_SPOP_SBC_1	650:654	Mutation rewiring degron network	0.0833
p.R655L	TCGA-AP-A1DK	UCEC	TCGA	VYSSS	DEG_SPOP_SBC_1	650:654	Mutation rewiring degron network	0.3056
p.R655L	DO42033	UCEC	ICGC	VYSSS	DEG_SPOP_SBC_1	650:654	Mutation rewiring degron network	0.3056
p.K645N	TCGA-DK-A6B6	BLCA	TCGA	VYSSS	DEG_SPOP_SBC_1	650:654	Mutation substituting flanking lysine	0.3056
p.K645N	DO48576	BLCA	ICGC	VYSSS	DEG_SPOP_SBC_1	650:654	Mutation substituting flanking lysine	0.3056

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*NOTE: the Kaplan plots were collected from OncoLnc