DegronMD - Q9UJ78(ZMYM5)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.N485K	TCGA-77-A5G3	LUSC	TCGA	PPSST	DEG_SPOP_SBC_1	489:493	Mutation rewiring degron network	0.2222
p.N485K	DO45456	LUSC	ICGC	PPSST	DEG_SPOP_SBC_1	489:493	Mutation rewiring degron network	0.2222
p.T479A	TCGA-AA-3811	COAD	TCGA	PPSST	DEG_SPOP_SBC_1	489:493	Mutation rewiring degron network	0.0556
p.T479A	DO7962	COAD	ICGC	PPSST	DEG_SPOP_SBC_1	489:493	Mutation rewiring degron network	0.0556
p.E484D	TCGA-AA-3984	COAD	TCGA	PPSST	DEG_SPOP_SBC_1	489:493	Mutation rewiring degron network	0.1944
p.E484D	TCGA-CA-6718	COAD	TCGA	PPSST	DEG_SPOP_SBC_1	489:493	Mutation rewiring degron network	0.1944
p.E484D	DO9002	COAD	ICGC	PPSST	DEG_SPOP_SBC_1	489:493	Mutation rewiring degron network	0.1944
p.E484D	DO7801	COAD	ICGC	PPSST	DEG_SPOP_SBC_1	489:493	Mutation rewiring degron network	0.1944
p.T493K	DO228937	LICA	ICGC	PPSST	DEG_SPOP_SBC_1	489:493	Mutation altering degron motif	0.7306
p.S491P	SIDM00475	Ovarian Carcinoma	GDSC	PPSST	DEG_SPOP_SBC_1	489:493	Mutation altering degron motif	0.6752
p.S491P	OV-56	ovary	COSMIC	PPSST	DEG_SPOP_SBC_1	489:493	Mutation altering degron motif	0.6752
p.T493M	SIDM00217	Colorectal Carcinoma	GDSC	PPSST	DEG_SPOP_SBC_1	489:493	Mutation altering degron motif	0.7423
p.T493M	ACH-000999	Colon/Colorectal Cancer	CCLE	PPSST	DEG_SPOP_SBC_1	489:493	Mutation altering degron motif	0.7423
p.T493M	SNU-1040	large intestine	COSMIC	PPSST	DEG_SPOP_SBC_1	489:493	Mutation altering degron motif	0.7423
p.D498Y	SIDM01569	Hepatocellular Carcinoma	GDSC	PPSST	DEG_SPOP_SBC_1	489:493	Mutation rewiring degron network	0.1944
p.D498Y	ACH-000734	Liver Cancer	CCLE	PPSST	DEG_SPOP_SBC_1	489:493	Mutation rewiring degron network	0.1944

Kaplan plot for ZMYM5 in

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons

ZMYM5

UniProt ID: Q9UJ78

Entrez ID: 9205

Protein name: Zinc finger MYM-type protein 5 (Zinc finger protein 198-like 1) (Zinc finger protein 237)

External links: UniprotKB HGNC RefSeq COSMIC

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Kaplan plot for ZMYM5 in