DegronMD - Q9UKP3(ITGB1BP2)

GO - Biological processes (BP): View more >>

GO - Molecular function (MF): View more >>

GO - Cellular component (CC): View more >>

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.K68E	TCGA-09-2053	OV	TCGA	PATSS	DEG_SPOP_SBC_1	78:82	Mutation substituting flanking lysine	0.1667
p.K68E	DO31060	OV	ICGC	PATSS	DEG_SPOP_SBC_1	78:82	Mutation substituting flanking lysine	0.1667
p.P78H	TCGA-91-6836	LUAD	TCGA	PATSS	DEG_SPOP_SBC_1	78:82	Mutation altering degron motif	0.7694
p.P78H	DO23854	LUAD	ICGC	PATSS	DEG_SPOP_SBC_1	78:82	Mutation altering degron motif	0.7694
p.L90M	TCGA-B5-A11E	UCEC	TCGA	PATSS	DEG_SPOP_SBC_1	78:82	Mutation rewiring degron network	0.1111
p.L90M	DO41644	UCEC	ICGC	PATSS	DEG_SPOP_SBC_1	78:82	Mutation rewiring degron network	0.1111
p.P70H	TCGA-UY-A9PF	BLCA	TCGA	PATSS	DEG_SPOP_SBC_1	78:82	Mutation rewiring degron network	0.1111
p.R83C	DO9924	COAD	ICGC	PATSS	DEG_SPOP_SBC_1	78:82	Mutation rewiring degron network	0.3056
p.V74L	DO36710	READ	ICGC	PATSS	DEG_SPOP_SBC_1	78:82	Mutation rewiring degron network	0.2222
p.P87S	DO41133	UCEC	ICGC	PATSS	DEG_SPOP_SBC_1	78:82	Mutation rewiring degron network	0.1944

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons