DegronMD - Q9UNA1(ARHGAP26)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.P698L	TCGA-Z2-A8RT	SKCM	TCGA	PTSST	DEG_SPOP_SBC_1	688:692	Mutation rewiring degron network	0.1667
p.P698L	DO51301	SKCM	ICGC	PTSST	DEG_SPOP_SBC_1	688:692	Mutation rewiring degron network	0.1667
p.M679T	DO233183	GACA	ICGC	PTSST	DEG_SPOP_SBC_1	688:692	Mutation rewiring degron network	0.0833
p.S685I	DO229035	LICA	ICGC	PTSST	DEG_SPOP_SBC_1	688:692	Mutation rewiring degron network	0.25
p.V699I	DO47112	RECA	ICGC	PTSST	DEG_SPOP_SBC_1	688:692	Mutation rewiring degron network	0.1389
p.V699I	DO46862	RECA	ICGC	PTSST	DEG_SPOP_SBC_1	688:692	Mutation rewiring degron network	0.1389
p.V699I	SIDM00845	Burkitt's Lymphoma	GDSC	PTSST	DEG_SPOP_SBC_1	688:692	Mutation rewiring degron network	0.1389
p.V699I	SIDM00262	Ewing's Sarcoma	GDSC	PTSST	DEG_SPOP_SBC_1	688:692	Mutation rewiring degron network	0.1389
p.V699I	SIDM00461	Acute Myeloid Leukemia	GDSC	PTSST	DEG_SPOP_SBC_1	688:692	Mutation rewiring degron network	0.1389
p.V699I	SIDM01519	Head and Neck Carcinoma	GDSC	PTSST	DEG_SPOP_SBC_1	688:692	Mutation rewiring degron network	0.1389
p.V699I	ES6	bone	COSMIC	PTSST	DEG_SPOP_SBC_1	688:692	Mutation rewiring degron network	0.1389
p.V699I	OCI-AML5	haematopoietic and lymphoid tissue	COSMIC	PTSST	DEG_SPOP_SBC_1	688:692	Mutation rewiring degron network	0.1389
p.P702Q	DO47578	SKCM	ICGC	PTSST	DEG_SPOP_SBC_1	688:692	Mutation rewiring degron network	0.0556
p.P702S	DO42977	UCEC	ICGC	PTSST	DEG_SPOP_SBC_1	688:692	Mutation rewiring degron network	0.0556
p.F685C	QIMR-WIL	haematopoietic and lymphoid tissue	COSMIC	PTSST	DEG_SPOP_SBC_1	688:692	Mutation rewiring degron network	0.25

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons