DegronMD - Q9UNW9(NOVA2)

NOVA2

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.V217M	TCGA-AF-2687	READ	TCGA	PQSSS	DEG_SPOP_SBC_1	204:208	Mutation rewiring degron network	0.0833
p.V217M	TCGA-EB-A6R0	SKCM	TCGA	PQSSS	DEG_SPOP_SBC_1	204:208	Mutation rewiring degron network	0.0833
p.V217M	DO36902	READ	ICGC	PQSSS	DEG_SPOP_SBC_1	204:208	Mutation rewiring degron network	0.0833
p.V217M	DO48646	SKCM	ICGC	PQSSS	DEG_SPOP_SBC_1	204:208	Mutation rewiring degron network	0.0833
p.V217M	SIDM01299	Colorectal Carcinoma	GDSC	PQSSS	DEG_SPOP_SBC_1	204:208	Mutation rewiring degron network	0.0833
p.D203E	TCGA-EI-6881	READ	TCGA	PQSSS	DEG_SPOP_SBC_1	204:208	Mutation rewiring degron network	0.3056
p.D203E	DO37098	READ	ICGC	PQSSS	DEG_SPOP_SBC_1	204:208	Mutation rewiring degron network	0.3056
p.S194N	DO230343	COCA	ICGC	PQSSS	DEG_SPOP_SBC_1	204:208	Mutation blocking phosphorylation signal	0.5
p.A215T	DO234199	ESAD	ICGC	PQSSS	DEG_SPOP_SBC_1	204:208	Mutation rewiring degron network	0.1389
p.V197M	DO16999	KIRC	ICGC	PQSSS	DEG_SPOP_SBC_1	204:208	Mutation rewiring degron network	0.1389
p.S194R	DO228952	LICA	ICGC	PQSSS	DEG_SPOP_SBC_1	204:208	Mutation blocking phosphorylation signal	0.5
p.Q205K	DO228974	LICA	ICGC	PQSSS	DEG_SPOP_SBC_1	204:208	Mutation altering degron motif	0.5833

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*NOTE: the Kaplan plots were collected from OncoLnc