DegronMD - Q9UNZ5(C19orf53)

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GO - Molecular function (MF): View more >>

GO - Cellular component (CC): View more >>

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.A84T	TCGA-AA-3833	COAD	TCGA	AATSS	DEG_SPOP_SBC_1	91:95	Mutation rewiring degron network	0.1389
p.A84T	DO9796	COAD	ICGC	AATSS	DEG_SPOP_SBC_1	91:95	Mutation rewiring degron network	0.1389
p.G88R	TCGA-EE-A29V	SKCM	TCGA	AATSS	DEG_SPOP_SBC_1	91:95	Mutation rewiring degron network	0.25
p.G88R	DO38006	SKCM	ICGC	AATSS	DEG_SPOP_SBC_1	91:95	Mutation rewiring degron network	0.25
p.A92T	DO233693	GACA	ICGC	AATSS	DEG_SPOP_SBC_1	91:95	Mutation altering degron motif	0.6028
p.P98L	DO220882	MELA	ICGC	AATSS	DEG_SPOP_SBC_1	91:95	Mutation rewiring degron network	0.25
p.S95F	DO218896	SKCA	ICGC	AATSS	DEG_SPOP_SBC_1	91:95	Mutation altering degron motif	0.7982
p.A82S	SIDM00313	Hodgkin's Lymphoma	GDSC	AATSS	DEG_SPOP_SBC_1	91:95	Mutation rewiring degron network	0.0833
p.A82S	ACH-000702	Lymphoma	CCLE	AATSS	DEG_SPOP_SBC_1	91:95	Mutation rewiring degron network	0.0833

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons