DegronMD - Q9UPN7(PPP6R1)

PPP6R1

Please click HERE for better display.

GO - Biological processes (BP): View more >>

GO - Molecular function (MF): View more >>

GO - Cellular component (CC): View more >>

Choose a PDB ID:
Open in full screen with detailed sequence annotations

Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.R823S	TCGA-44-2659	LUAD	TCGA	APSSS	DEG_SPOP_SBC_1	814:818	Mutation rewiring degron network	0.1944
p.R823S	DO23744	LUAD	ICGC	APSSS	DEG_SPOP_SBC_1	814:818	Mutation rewiring degron network	0.1944
p.R823G	TCGA-49-AARE	LUAD	TCGA	APSSS	DEG_SPOP_SBC_1	814:818	Mutation rewiring degron network	0.1944
p.R823G	DO218922	LUAD	ICGC	APSSS	DEG_SPOP_SBC_1	814:818	Mutation rewiring degron network	0.1944
p.H809R	TCGA-85-8664	LUSC	TCGA	APSSS	DEG_SPOP_SBC_1	814:818	Mutation rewiring degron network	0.1944
p.H809R	DO45469	LUSC	ICGC	APSSS	DEG_SPOP_SBC_1	814:818	Mutation rewiring degron network	0.1944
p.G810R	TCGA-AP-A0LM	UCEC	TCGA	APSSS	DEG_SPOP_SBC_1	814:818	Mutation rewiring degron network	0.2222
p.G810R	DO43306	UCEC	ICGC	APSSS	DEG_SPOP_SBC_1	814:818	Mutation rewiring degron network	0.2222
p.S826Y	TCGA-ER-A196	SKCM	TCGA	APSSS	DEG_SPOP_SBC_1	814:818	Mutation rewiring degron network	0.1111
p.S826Y	DO47474	SKCM	ICGC	APSSS	DEG_SPOP_SBC_1	814:818	Mutation rewiring degron network	0.1111
p.T827I	TCGA-PK-A5HB	ACC	TCGA	APSSS	DEG_SPOP_SBC_1	814:818	Mutation rewiring degron network	0.0833
p.S816R	DO229027	LICA	ICGC	APSSS	DEG_SPOP_SBC_1	814:818	Mutation altering degron motif	0.8538
p.S817F	DO37474	SKCM	ICGC	APSSS	DEG_SPOP_SBC_1	814:818	Mutation altering degron motif	0.9093
p.S818L	SIDM01087	Melanoma	GDSC	APSSS	DEG_SPOP_SBC_1	814:818	Mutation altering degron motif	0.7667

Select cancer type:
Download patient class data (Lower:Upper = 50%:50%)

*NOTE: the Kaplan plots were collected from OncoLnc