DegronMD - Q9UPT9(USP22)

USP22

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.L341P	TCGA-AP-A1DK	UCEC	TCGA	PGSST	DEG_SPOP_SBC_1	332:336	Mutation rewiring degron network	0.1944
p.L341P	DO42033	UCEC	ICGC	PGSST	DEG_SPOP_SBC_1	332:336	Mutation rewiring degron network	0.1944
p.P337L	TCGA-D3-A51R	SKCM	TCGA	PGSST	DEG_SPOP_SBC_1	332:336	Mutation rewiring degron network	0.3056
p.P337L	DO47480	SKCM	ICGC	PGSST	DEG_SPOP_SBC_1	332:336	Mutation rewiring degron network	0.3056
p.P340T	DO229026	LICA	ICGC	PGSST	DEG_SPOP_SBC_1	332:336	Mutation rewiring degron network	0.2222
p.S342R	DO229026	LICA	ICGC	PGSST	DEG_SPOP_SBC_1	332:336	Mutation rewiring degron network	0.1667
p.P340L	DO37827	SKCM	ICGC	PGSST	DEG_SPOP_SBC_1	332:336	Mutation rewiring degron network	0.2222
p.D322N	ACH-000990	Endometrial/Uterine Cancer	CCLE	PGSST	DEG_SPOP_SBC_1	332:336	Mutation rewiring degron network	0.0556
p.P323L	ACH-001335	Cervical Cancer	CCLE	PGSST	DEG_SPOP_SBC_1	332:336	Mutation rewiring degron network	0.0833
p.N336K	NCI-H1155	lung	COSMIC	PGSST	DEG_SPOP_SBC_1	332:336	Mutation altering degron motif	0.6918

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*NOTE: the Kaplan plots were collected from OncoLnc