DegronMD - Q9Y2W3(SLC45A1)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.R37Q	TCGA-A6-A565	COAD	TCGA	AASST	DEG_SPOP_SBC_1	38:42	Mutation rewiring degron network	0.3056
p.R37Q	DO44090	COAD	ICGC	AASST	DEG_SPOP_SBC_1	38:42	Mutation rewiring degron network	0.3056
p.T36I	TCGA-CG-4442	STAD	TCGA	AASST	DEG_SPOP_SBC_1	38:42	Mutation rewiring degron network	0.2778
p.G30S	TCGA-D3-A51T	SKCM	TCGA	AASST	DEG_SPOP_SBC_1	38:42	Mutation rewiring degron network	0.1111
p.G30S	DO47389	SKCM	ICGC	AASST	DEG_SPOP_SBC_1	38:42	Mutation rewiring degron network	0.1111
p.R52M	TCGA-EY-A215	UCEC	TCGA	AASST	DEG_SPOP_SBC_1	38:42	Mutation rewiring degron network	0.0556
p.R52M	DO42665	UCEC	ICGC	AASST	DEG_SPOP_SBC_1	38:42	Mutation rewiring degron network	0.0556
p.P50H	DO223730	DLBC	ICGC	AASST	DEG_SPOP_SBC_1	38:42	Mutation rewiring degron network	0.1111
p.L48I	DO26025	LUAD	ICGC	AASST	DEG_SPOP_SBC_1	38:42	Mutation rewiring degron network	0.1667
p.G45V	DO26790	LUSC	ICGC	AASST	DEG_SPOP_SBC_1	38:42	Mutation rewiring degron network	0.25
p.A43T	DO220891	MELA	ICGC	AASST	DEG_SPOP_SBC_1	38:42	Mutation rewiring degron network	0.3056
p.A47S	DO50662	ORCA	ICGC	AASST	DEG_SPOP_SBC_1	38:42	Mutation rewiring degron network	0.1944
p.R28H	DO232224	PBCA	ICGC	AASST	DEG_SPOP_SBC_1	38:42	Mutation rewiring degron network	0.0556
p.P29T	SIDM00151	Ovarian Carcinoma	GDSC	AASST	DEG_SPOP_SBC_1	38:42	Mutation rewiring degron network	0.0833
p.P29T	IGROV-1	ovary	COSMIC	AASST	DEG_SPOP_SBC_1	38:42	Mutation rewiring degron network	0.0833
p.P43L	SIDM00738	Non-Small Cell Lung Carcinoma	GDSC	AASST	DEG_SPOP_SBC_1	38:42	Mutation rewiring degron network	0.3056
p.P43L	NCI-H1755	lung	COSMIC	AASST	DEG_SPOP_SBC_1	38:42	Mutation rewiring degron network	0.3056

Kaplan plot for SLC45A1 in

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons

SLC45A1

UniProt ID: Q9Y2W3

Entrez ID: 50651

Protein name: Proton-associated sugar transporter A (PAST-A) (Deleted in neuroblastoma 5 protein) (DNb-5) (Solute carrier family 45 member 1)

External links: UniprotKB HGNC RefSeq COSMIC

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Kaplan plot for SLC45A1 in