DegronMD - Q9Y388(RBMX2)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.V179A	TCGA-AX-A1CE	UCEC	TCGA	PSSSS	DEG_SPOP_SBC_1	184:188	Mutation rewiring degron network	0.1944
p.V179A	DO42280	UCEC	ICGC	PSSSS	DEG_SPOP_SBC_1	184:188	Mutation rewiring degron network	0.1944
p.S187L	TCGA-B5-A3FC	UCEC	TCGA	PSSSS	DEG_SPOP_SBC_1	184:188	Mutation altering degron motif	0.8778
p.S187L	TCGA-CG-5721	STAD	TCGA	PSSSS	DEG_SPOP_SBC_1	184:188	Mutation altering degron motif	0.8778
p.S187L	TCGA-EO-A3AY	UCEC	TCGA	PSSSS	DEG_SPOP_SBC_1	184:188	Mutation altering degron motif	0.8778
p.S187L	TCGA-O2-A52V	LUSC	TCGA	PSSSS	DEG_SPOP_SBC_1	184:188	Mutation altering degron motif	0.8778
p.S187L	DO219223	LUSC	ICGC	PSSSS	DEG_SPOP_SBC_1	184:188	Mutation altering degron motif	0.8778
p.S187L	DO38192	STAD	ICGC	PSSSS	DEG_SPOP_SBC_1	184:188	Mutation altering degron motif	0.8778
p.S187L	DO43202	UCEC	ICGC	PSSSS	DEG_SPOP_SBC_1	184:188	Mutation altering degron motif	0.8778
p.S187L	DO41871	UCEC	ICGC	PSSSS	DEG_SPOP_SBC_1	184:188	Mutation altering degron motif	0.8778
p.R191C	TCGA-BR-4184	STAD	TCGA	PSSSS	DEG_SPOP_SBC_1	184:188	Mutation rewiring degron network	0.25
p.R191C	TCGA-EO-A22X	UCEC	TCGA	PSSSS	DEG_SPOP_SBC_1	184:188	Mutation rewiring degron network	0.25
p.R191C	DO38328	STAD	ICGC	PSSSS	DEG_SPOP_SBC_1	184:188	Mutation rewiring degron network	0.25
p.R191C	DO43907	UCEC	ICGC	PSSSS	DEG_SPOP_SBC_1	184:188	Mutation rewiring degron network	0.25
p.R191H	TCGA-BR-4256	STAD	TCGA	PSSSS	DEG_SPOP_SBC_1	184:188	Mutation rewiring degron network	0.25
p.R191H	TCGA-IB-7651	PAAD	TCGA	PSSSS	DEG_SPOP_SBC_1	184:188	Mutation rewiring degron network	0.25
p.R191H	TCGA-VQ-A91D	STAD	TCGA	PSSSS	DEG_SPOP_SBC_1	184:188	Mutation rewiring degron network	0.25
p.R191H	DO46657	PAAD	ICGC	PSSSS	DEG_SPOP_SBC_1	184:188	Mutation rewiring degron network	0.25
p.R191H	DO38743	STAD	ICGC	PSSSS	DEG_SPOP_SBC_1	184:188	Mutation rewiring degron network	0.25
p.R191H	DO51783	STAD	ICGC	PSSSS	DEG_SPOP_SBC_1	184:188	Mutation rewiring degron network	0.25
p.R190S	TCGA-CN-6992	HNSC	TCGA	PSSSS	DEG_SPOP_SBC_1	184:188	Mutation rewiring degron network	0.2778
p.R190S	DO14606	HNSC	ICGC	PSSSS	DEG_SPOP_SBC_1	184:188	Mutation rewiring degron network	0.2778
p.D176E	DO225165	BRCA	ICGC	PSSSS	DEG_SPOP_SBC_1	184:188	Mutation rewiring degron network	0.1111
p.E182Q	DO223026	ESCA	ICGC	PSSSS	DEG_SPOP_SBC_1	184:188	Mutation rewiring degron network	0.2778

Kaplan plot for RBMX2 in

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons

RBMX2

UniProt ID: Q9Y388

Entrez ID: 51634

Protein name: RNA-binding motif protein, X-linked 2

External links: UniprotKB HGNC RefSeq COSMIC

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Kaplan plot for RBMX2 in