DegronMD - Q9Y4F4(TOGARAM1)

TOGARAM1

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.S81I	SIDM01282	Colorectal Carcinoma	GDSC	AVSSS	DEG_SPOP_SBC_1	77:81	Mutation altering degron motif	0.7341
p.S1083L	SIDM00831	Head and Neck Carcinoma	GDSC	AGSSS	DEG_SPOP_SBC_1	1079:1083	Mutation altering degron motif	0.7667
p.S1083L	Detroit562	upper aerodigestive tract	COSMIC	AGSSS	DEG_SPOP_SBC_1	1079:1083	Mutation altering degron motif	0.7667
p.L67V	SIDM00041	Gastric Carcinoma	GDSC	PTTTS	DEG_SPOP_SBC_1	61:65	Mutation rewiring degron network	0.2778
p.L67V	SIDM00041	Gastric Carcinoma	GDSC	AVSSS	DEG_SPOP_SBC_1	77:81	Mutation rewiring degron network	0.0556
p.L67V	SIDM00170	Head and Neck Carcinoma	GDSC	PTTTS	DEG_SPOP_SBC_1	61:65	Mutation rewiring degron network	0.2778
p.L67V	SIDM00170	Head and Neck Carcinoma	GDSC	AVSSS	DEG_SPOP_SBC_1	77:81	Mutation rewiring degron network	0.0556
p.L67V	STS-0421	soft tissue	COSMIC	PTTTS	DEG_SPOP_SBC_1	61:65	Mutation rewiring degron network	0.2778
p.L67V	STS-0421	soft tissue	COSMIC	AVSSS	DEG_SPOP_SBC_1	77:81	Mutation rewiring degron network	0.0556
p.A54T	SIDM00837	Colorectal Carcinoma	GDSC	PTTTS	DEG_SPOP_SBC_1	61:65	Mutation rewiring degron network	0.1389
p.A54T	SW48	large intestine	COSMIC	PTTTS	DEG_SPOP_SBC_1	61:65	Mutation rewiring degron network	0.1389

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*NOTE: the Kaplan plots were collected from OncoLnc